(+)-Blebbistatin

• 常用名: (+)-Blebbistatin
• 英文名: (+)-Blebbistatin
• CAS号: 1177356-70-5
• 分子量: 292.332
• 密度: 1.3±0.1 g/cm3
• 沸点: 507.3±60.0 °C at 760 mmHg
• 分子式: C₁₈H₁₆N₂O₂
• 熔点: N/A
• 闪点: 260.6±32.9 °C

(+)-Blebbistatin用途

(+)-Blebbistatin 是 (–)-Blebbistatin 的非活性对映异构体。(–)-Blebbistatin 是选择性的非肌肉肌球蛋白 II (myosin II) ATPase 活性的抑制剂。

(+)-Blebbistatin名称

• 英文名: (R)-(+)-Blebbistatin

(+)-Blebbistatin生物活性

• 描述: (+)-Blebbistatin 是 (–)-Blebbistatin 的非活性对映异构体。(–)-Blebbistatin 是选择性的非肌肉肌球蛋白 II (myosin II) ATPase 活性的抑制剂。
• 相关类别:
  信号通路 >> 细胞骨架 >> 肌球蛋白
  研究领域 >> 其他
• 参考文献:

  [1]. Cristina Lucas‐Lopez, et al. Absolute Stereochemical Assignment and Fluorescence Tuning of the Small Molecule Tool, (–)‐Blebbistatin.

(+)-Blebbistatin物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 507.3±60.0 °C at 760 mmHg
• 分子式: C₁₈H₁₆N₂O₂
• 分子量: 292.332
• 闪点: 260.6±32.9 °C
• 精确质量: 292.121185
• PSA: 52.90000
• LogP: 1.62
• InChIKey: LZAXPYOBKSJSEX-SFHVURJKSA-N
• SMILES: Cc1ccc2c(c1)C(=O)C1(O)CCN(c3ccccc3)C1=N2
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.681
• 储存条件: -20°C，密闭，干燥

(+)-Blebbistatin靶点实验

查看更多实验

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Immunotoxin (SS1P) sensitization/mitigation study - treatment arm 来源：NCGC 靶标：N/A External Id：MSKB3SS1P200

实验名称：Immunotoxin (HA22) sensitization/mitigation study. Vehicle arm (PBS) 来源：NCGC 靶标：N/A External Id：MS-ITOX-NALM6-HA22

实验名称：qHTS Assay for Identifying Gametocytocidal Compounds 来源：NCGC 靶标：N/A External Id：MALG0567

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：Immunotoxin (SS1P) sensitization/mitigation study. Vehicle arm (DMEM) 来源：NCGC 靶标：N/A External Id：MS-ITOX-KB3DMEM

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

实验名称：Immunotoxin (HA22) sensitization/mitigation study - treatment arm (low dose) 来源：NCGC 靶标：N/A External Id：NALM6HA22

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(+)-Blebbistatin英文别名

• (−)-Blebbistatin
• (3aR)-3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
• (3aR)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one
• Blebbistatin
• (3aS)-3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
• (+)-Blebbistatin
• (S)-Blebbistatin