SC-41930

• 常用名: SC-41930
• 英文名: SC-41930
• CAS号: 120072-59-5
• 分子量: 484.58100
• 密度: 1.156g/cm3
• 沸点: 658ºC at 760mmHg
• 分子式: C₂₈H₃₆O₇
• 熔点: N/A
• 闪点: 214.1ºC

SC-41930用途

SC-41930 是一种口服活性的 eukotriene-B4 receptor 拮抗剂。SC-41930可减轻豚鼠醋酸致结肠炎症模型的炎症反应。

SC-41930名称

• 英文名: 7-[3-(4-acetyl-3-methoxy-2-propylphenoxy)propoxy]-8-propyl-3,4-dihydro-2H-chromene-2-carboxylic acid

SC-41930生物活性

• 描述: SC-41930 是一种口服活性的 eukotriene-B4 receptor 拮抗剂。SC-41930可减轻豚鼠醋酸致结肠炎症模型的炎症反应。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 白三烯受体
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Fretland DJ, et al. The effect of leukotriene-B4 receptor antagonist, SC-41930, on acetic acid-induced colonic inflammation. Agents Actions. 1989;27(3-4):395-397.

SC-41930物理化学性质

• 密度: 1.156g/cm3
• 沸点: 658ºC at 760mmHg
• 分子式: C₂₈H₃₆O₇
• 分子量: 484.58100
• 闪点: 214.1ºC
• 精确质量: 484.24600
• PSA: 91.29000
• LogP: 5.42890
• InChIKey: ZVVCSBSDFGYRCB-UHFFFAOYSA-N
• SMILES: CCCc1c(OCCCOc2ccc(C(C)=O)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2
• 蒸汽压: 3.27E-18mmHg at 25°C
• 折射率: 1.549

SC-41930靶点实验

查看更多实验

实验名称：Inhibition of specific binding of [3H]-LTB4 to LTB4 receptor in guinea pig lung membr... 来源：ChEMBL 靶标：Leukotriene B4 receptor 2 External Id：CHEMBL709169

实验名称：Inhibition of binding to the leukotriene D4 receptor at 1*10e-5 M concentration 来源：ChEMBL 靶标：Cysteinyl leukotriene receptor 1 External Id：CHEMBL664799

实验名称：Oral effective dose for guinea pig LTB4 induced intradermal chemotaxis 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL686635

实验名称：Inhibition of LTB4 induced expression of human neutrophil integrin CD11b/CD18. 来源：ChEMBL 靶标：Leukotriene B4 receptor 2 External Id：CHEMBL699620

实验名称：Topical effective dose for TPA induced ear inflammation in the mouse 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL720918

实验名称：Inhibition of specific binding of [3H]LTB4 to LTB4 receptor in human neutrophils 来源：ChEMBL 靶标：Leukotriene B4 receptor 2 External Id：CHEMBL873016

实验名称：Oral effective dose for TPA induced ear inflammation in the mouse 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL721365

实验名称：Compound was tested for inhibitory activity against leukotriene B4 induced neutrophil... 来源：ChEMBL 靶标：Homo sapiens External Id：CHEMBL842236

实验名称：Binding affinity towards Leukotriene B4 receptor guinea pig lung membrane using [3H]L... 来源：ChEMBL 靶标：Leukotriene B4 receptor 2 External Id：CHEMBL704379

实验名称：Topical effective dose when coapplied with phorbol ester (PMA) was assessed by ear we... 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL689236

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SC-41930英文别名

• 2H-1-Benzopyran-2-carboxylicacid,7-[3-(4-acetyl-3-methoxy-2-propylphenoxy)propoxy]-3,4-dihydro-8-propyl
• BioMed 101
• 7-[3-(4-acetyl-3-methoxy-2-propylphenoxy)-propoxy]-3,4-dihydro-8-propyl-2H-1-benzopyran-2-carboxylic acid