比阿培南

• 常用名: 比阿培南
• 英文名: Biapenem
• CAS号: 120410-24-4
• 分子量: 350.393
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₅H₁₈N₄O₄S
• 熔点: 265-271°C (dec.)
• 闪点: N/A

比阿培南用途

【用途一】
为全合成的沙星类抗菌药

比阿培南名称

• 中文名: 比阿培南
• 英文名: biapenem
• 中文别名: 比亚培南 | 6-[[(4R,5S,6S)-2-羧基-6-((1R)-1-羟乙基)-4-甲基-7-氧代-1-氮杂双环[3.2.0]庚-2-烯-3-基]硫]-6,7-双氢-5H-哌唑酮[1,2-a][1,2,4]三氮杂-4-内盐 | 比阿培南

比阿培南生物活性

• 描述: Biapenem是不经肠道的广谱碳青霉烯抗生素。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 感染
• 参考文献:

  [1]. Perry, C.M. and T. Ibbotson, Biapenem. Drugs, 2002. 62(15): p. 2221-34; discussion 2235.

  [2]. Kasahara, S., et al., [Clinical effects of biapenem on febrile neutropenia in patients with hematological malignancy]. Jpn J Antibiot, 2008. 61(3): p. 115-21.

比阿培南物理化学性质

• 熔点: 265-271°C (dec.)
• 分子式: C₁₅H₁₈N₄O₄S
• 分子量: 350.393
• 精确质量: 350.104889
• PSA: 127.67000
• InChIKey: MRMBZHPJVKCOMA-YJFSRANCSA-N
• SMILES: CC(O)C1C(=O)N2C(C(=O)[O-])=C(SC3Cn4cnc[n+]4C3)C(C)C12
• 外观性状: 白色至淡黄色粉末
• 折射率: 1.651
• 储存条件: -20?C Freezer

比阿培南安全信息

• 危险品运输编码: NONH for all modes of transport

比阿培南靶点实验

查看更多实验

实验名称：Minimum inhibitory concentration required for antibacterial activity against Escheric... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL678940

实验名称：Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2X preincubated f... 来源：ChEMBL 靶标：Penicillin-binding protein 2x External Id：CHEMBL1053624

实验名称：Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2X preincubated for... 来源：ChEMBL 靶标：Penicillin-binding protein 2X External Id：CHEMBL1053623

实验名称：Ratio of Kcat to Km for Pseudomonas aeruginosa beta-lactamaseVIM-2 by UV spectrophoto... 来源：ChEMBL 靶标：Beta-lactamase class B VIM-2 External Id：CHEMBL1676796

实验名称：Tmax in epithelial lining fluid of healthy human at 0.3 gm/kg, iv after 0.5 hrs 来源：ChEMBL 靶标：N/A External Id：CHEMBL1667039

实验名称：Tmax in epithelial lining fluid of healthy human at 0.3 gm/kg, iv after 3 hrs 来源：ChEMBL 靶标：N/A External Id：CHEMBL1667040

实验名称：AUC in epithelial lining fluid of healthy human at 0.3 gm/kg, iv after 0.5 hrs 来源：ChEMBL 靶标：N/A External Id：CHEMBL1667041

实验名称：Antibacterial activity against Enterobacter cloacae ECL1058 expressing KPC3/SHV-11/TE... 来源：ChEMBL 靶标：Enterobacter cloacae External Id：CHEMBL3580387

实验名称：Minimum inhibitory concentration required for antibacterial activity against Staphylo... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL804481

实验名称：AUC in epithelial lining fluid of healthy human at 0.3 gm/kg, iv after 3 hrs 来源：ChEMBL 靶标：N/A External Id：CHEMBL1667042

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比阿培南英文别名

• Biapenem (JAN/USAN)
• EINECS 204-352-8
• 5H-Pyrazolo[1,2-a][1,2,4]triazol-4-ium, 6-[[(4R,5S,6S)-2-carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-, inner salt
• BiapeneM Crude
• Biapenem [USAN:INN]
• (4R,5S,6S)-3-(6,7-Dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-ylsulfanyl)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
• [4R-[4a,5b,6b(R*)]]-6-[[2-Carboxy-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-5 H-pyrazolo[1,2-a][1,2,4]triazol-4-ium inner salt
• LJ C10627
• omegacin
• MFCD00864863
• Biapenem
• LJ C10,627
• Biapenern
• L-627