CGP 20712 dihydrochloride

• 常用名: CGP 20712 dihydrochloride
• 英文名: CGP 20712 dihydrochloride
• CAS号: 1216905-73-5
• 分子量: 567.39
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₇Cl₂F₃N₄O₅
• 熔点: N/A
• 闪点: N/A

CGP 20712 dihydrochloride用途

CGP 20712 dihydrochloride 是 β 3-adrenoceptor 的拮抗剂。CGP 20712 dihydrochloride 对异丙肾上腺素有抑制作用,IC50 为 79 μM。

CGP 20712 dihydrochloride名称

• 英文名: 2-Hydroxy-5-{2-[(2-hydroxy-3-{4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy}propyl)amino]ethoxy}benzamide dihydrochloride

CGP 20712 dihydrochloride生物活性

• 描述: CGP 20712 dihydrochloride 是 β 3-adrenoceptor 的拮抗剂。CGP 20712 dihydrochloride 对异丙肾上腺素有抑制作用,IC50 为 79 μM。
• 相关类别:
  研究领域 >> 内分泌
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Van Liefde I, et al. Isoproterenol and selective agonists stimulate similar atypical beta-adrenoceptors in rat adipocytes. Biochem Pharmacol. 1993 Feb 24;45(4):974-7.

CGP 20712 dihydrochloride物理化学性质

• 分子式: C₂₃H₂₇Cl₂F₃N₄O₅
• 分子量: 567.39
• 精确质量: 566.131042
• InChIKey: PURFQCFKYNMIQF-UHFFFAOYSA-N
• SMILES: Cl.Cl.Cn1cc(C(F)(F)F)nc1-c1ccc(OCC(O)CNCCOc2ccc(O)c(C(N)=O)c2)cc1

CGP 20712 dihydrochloride靶点实验

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实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

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CGP 20712 dihydrochloride英文别名

• Benzamide, 2-hydroxy-5-[2-[[2-hydroxy-3-[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy]propyl]amino]ethoxy]-, hydrochloride (1:2)
• 2-Hydroxy-5-{2-[(2-hydroxy-3-{4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy}propyl)amino]ethoxy}benzamide dihydrochloride