Ganirelix Acetate

更新时间:2024-01-06 19:04:48

Ganirelix Acetate结构式
Ganirelix Acetate结构式
品牌特惠专场
常用名 Ganirelix Acetate 英文名 Ganirelix Acetate
CAS号 129311-55-3 分子量 1690.423
密度 N/A 沸点 N/A
分子式 C84H121ClN18O17 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

 Ganirelix Acetate用途


醋酸甘乃瑞利(Ganirelix醋酸盐,Ganirest)是一种可注射竞争性促性腺激素释放激素(GnRH)拮抗剂。甘乃瑞利醋酸盐直接与内源性分子竞争受体结合,并导致雌二醇水平迅速降低。甘乃瑞利醋酸盐可用于研究卵巢过度刺激综合征(OHSS)[1]。

 Ganirelix Acetate名称

英文名 Ganirelix acetate
英文别名 更多

 Ganirelix Acetate生物活性

描述 醋酸甘乃瑞利(Ganirelix醋酸盐,Ganirest)是一种可注射竞争性促性腺激素释放激素(GnRH)拮抗剂。甘乃瑞利醋酸盐直接与内源性分子竞争受体结合,并导致雌二醇水平迅速降低。甘乃瑞利醋酸盐可用于研究卵巢过度刺激综合征(OHSS)[1]。
相关类别
靶点

GnRH[1]

参考文献

[1]. Gustofson RL, et al. Ganirelix acetate causes a rapid reduction in estradiol levels without adversely affecting oocyte maturation in women pretreated with leuprolide acetate who are at risk of ovarian hyperstimulation syndrome. Hum Reprod. 2006 Nov;21(11):2830-7.

 Ganirelix Acetate物理化学性质

分子式 C84H121ClN18O17
分子量 1690.423
精确质量 1688.884521
储存条件 -20°C,密闭,干燥

 Ganirelix Acetate安全信息

符号 GHS07
GHS07
信号词 Warning
危害声明 H315-H319-H335
警示性声明 P261-P305 + P351 + P338
危险品运输编码 NONH for all modes of transport

 Ganirelix Acetate文献27

更多文献
Androgens influence microvascular dilation in PCOS through ET-A and ET-B receptors.

Am. J. Physiol. Endocrinol. Metab. 305(7) , E818-25, (2013)

Hyperandrogenism and vascular dysfunction often coexist in women with polycystic ovary syndrome (PCOS). We hypothesized that testosterone compromises cutaneous microvascular dilation in women with PCO...

GnRH antagonist versus long GnRH agonist protocol in poor IVF responders: a randomized clinical trial.

Eur. J. Obstet. Gynecol. Reprod. Biol. 166(1) , 43-6, (2013)

To compare the efficacy of the long GnRH agonist and the fixed GnRH antagonist protocols in IVF poor responders.This was a randomized controlled trial performed in the Iakentro IVF centre, Thessalonik...

Outpatient management of severe early OHSS by administration of GnRH antagonist in the luteal phase: an observational cohort study.

Reprod. Biol. Endocrinol. 10 , 69, (2012)

Management of established severe OHSS requires prolonged hospitalization, occasionally in intensive care units, accompanied by multiple ascites punctures, correction of intravascular fluid volume and ...

 Ganirelix Acetate英文别名

56U7906FQW
D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]- ;L-lysyl-L-prolyl-, acetate (1:2)
Ganirelix acetate
UNII:56U7906FQW
N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-D- ;alaninamide acetate (1:2)
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