Restrictocin
Restrictocin结构式
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常用名 | Restrictocin | 英文名 | Restrictocin |
|---|---|---|---|---|
| CAS号 | 1406-72-0 | 分子量 | 355.474 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 577.7±50.0 °C at 760 mmHg | |
| 分子式 | C21H29N3O2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 303.2±30.1 °C | |
| 符号 |
GHS07, GHS08 |
信号词 | Danger |
Restrictocin用途Restrictocin是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。 |
| 英文名 | 4-(1-Isobutyl-1,3,4,9-tetrahydro-2H-β-carbolin-2-yl)-N,N-dimethyl-4-oxobutanamide |
|---|---|
| 英文别名 | 更多 |
| 密度 | 1.1±0.1 g/cm3 |
|---|---|
| 沸点 | 577.7±50.0 °C at 760 mmHg |
| 分子式 | C21H29N3O2 |
| 分子量 | 355.474 |
| 闪点 | 303.2±30.1 °C |
| 精确质量 | 355.225983 |
| LogP | 2.79 |
| 蒸汽压 | 0.0±1.6 mmHg at 25°C |
| 折射率 | 1.582 |
| 符号 |
GHS07, GHS08 |
|---|---|
| 信号词 | Danger |
| 危害声明 | H302-H312-H317-H332-H334 |
| 警示性声明 | P261-P280-P342 + P311 |
| 个人防护装备 | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| 危险品运输编码 | NONH for all modes of transport |
| RTECS号 | VH4725000 |
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The ribotoxin restrictocin recognizes its RNA substrate by selective engagement of active site residues.
Biochemistry 50(14) , 3004-13, (2011) Restrictocin and related fungal endoribonucleases from the α-sarcin family site-specifically cleave the sarcin/ricin loop (SRL) on the ribosome to inhibit translation and ultimately trigger cell death... |
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Role of individual cysteine residues and disulfide bonds in the structure and function of Aspergillus ribonucleolytic toxin restrictocin.
Biochemistry 38(31) , 10052-8, (1999) Restrictocin, produced by the fungus Aspergillus restrictus, belongs to the group of ribonucleolytic toxins called ribotoxins. It specifically cleaves a single phosphodiester bond in a conserved stem ... |
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Mechanism of specific target recognition and RNA hydrolysis by ribonucleolytic toxin restrictocin.
Biochemistry 40(31) , 9115-24, (2001) Restrictocin, a member of the fungal ribotoxin family, specifically cleaves a single phosphodiester bond in the 28S rRNA and potently inhibits eukaryotic protein synthesis. Residues Tyr47, His49, Glu9... |
| 2H-Pyrido[3,4-b]indole-2-butanamide, 1,3,4,9-tetrahydro-N,N-dimethyl-1-(2-methylpropyl)-γ-oxo- |
| 4-(1-Isobutyl-1,3,4,9-tetrahydro-2H-β-carbolin-2-yl)-N,N-dimethyl-4-oxobutanamide |
