13-乙酰基-9-羟基巴卡丁III

• 常用名: 13-乙酰基-9-羟基巴卡丁III
• 英文名: 9-Dihydro-13-acetylbaccatin III
• CAS号: 142203-65-4
• 分子量: 630.68
• 密度: 1.3±0.1 g/cm3
• 沸点: 601.4±55.0 °C at 760 mmHg
• 分子式: C₃₃H₄₂O₁₂
• 熔点: N/A
• 闪点: 193.0±25.0 °C

13-乙酰基-9-羟基巴卡丁III用途

9-Dihydro-13-acetylbaccatin III (9-DHAB III)是制备紫杉醇类似物的中间体。

13-乙酰基-9-羟基巴卡丁III名称

• 中文名: 13-乙酰基-9-羟基巴卡丁III
• 英文名: 13-Acetyl-9-dihydrobaccatin III
• 中文别名: 13-乙酰基-9-羟基巴卡丁 III | 9-DHB,13-乙酰基-9-羟基巴卡丁

13-乙酰基-9-羟基巴卡丁III生物活性

• 描述: 9-Dihydro-13-acetylbaccatin III (9-DHAB III)是制备紫杉醇类似物的中间体。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 癌症
• 参考文献:

  [1]. Li S, Zhang P, Zhang M, Fu C, Yu L. Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis. Plant Biol (Stuttg). 2013 Jan;15(1):19-26.

  [2]. Naill MC, Kolewe ME, Roberts SC. Paclitaxel uptake and transport in Taxus cell suspension cultures. Biochem Eng J. 2012 Apr 15;63:50-56.

  [3]. Qayum M, Nisar M, Shah MR, et al. Analgesic and antiinflammatory activities of taxoids from Taxus wallichiana Zucc. Phytother Res. 2012 Apr;26(4):552-6.

  [4]. Kevin Walker and Rodney Croteau. Taxol biosynthesis: Molecular cloning of a benzoyl- CoA:taxane 2α-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli. PNAS, 2000 , 97（25）：13591-13596.

13-乙酰基-9-羟基巴卡丁III物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 601.4±55.0 °C at 760 mmHg
• 分子式: C₃₃H₄₂O₁₂
• 分子量: 630.68
• 闪点: 193.0±25.0 °C
• PSA: 148.82000
• LogP: 0.69
• InChIKey: WPPPFZJNKLMYBW-FAEUQDRCSA-N
• SMILES: CC(=O)OC1CC2(O)C(OC(=O)c3ccccc3)C3C4(OC(C)=O)COC4CC(O)C3(C)C(O)C(OC(C)=O)C(=C1C)C2(C)C
• 蒸汽压: 0.0±3.9 mmHg at 25°C
• 折射率: 1.567
• 储存条件: 2-8°C

13-乙酰基-9-羟基巴卡丁III安全信息

• 危害码 (欧洲): Xi
• 危险品运输编码: UN 1544
• WGK德国: 3
• 包装等级: III
• 危险类别: 6.1(b)

13-乙酰基-9-羟基巴卡丁III靶点实验

查看更多实验

实验名称：Antiproliferative activity against mouse P388 cells by MTT assay 来源：ChEMBL 靶标：P388 External Id：CHEMBL948646

实验名称：Actual inhibitory activity in P388 leukemia cells by CoMFA analysis, expressed as log... 来源：ChEMBL 靶标：P388 External Id：CHEMBL766206

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13-乙酰基-9-羟基巴卡丁III英文别名

• 9-dehydro-13-acetylbaccatin III
• 7,9-Dideacetyl baccatin VI
• Ddabvi
• (1β,5β,7β,9α,10β,13α)-1,7,9-Trihydroxy-5,20-epoxytax-11-ene-4,10,13-triyl triacetate
• CS-1097
• 9-Dihydro-13-acetylbaccatin III