紫苏酮

• 常用名: 紫苏酮
• 英文名: Sageone
• CAS号: 142546-15-4
• 分子量: 300.39
• 密度: 1.20±0.1 g/cm3
• 沸点: N/A
• 分子式: C₁₉H₂₄O₃
• 熔点: N/A
• 闪点: N/A

紫苏酮用途

鼠尾草酮是从迷迭香中分离得到的一种二萜,是一种抗病毒和抗癌剂[1]。

紫苏酮名称

• 中文名: 紫苏酮
• 英文名: Sageone
• 中文别名: 鼠尾草酮

紫苏酮生物活性

• 描述: 鼠尾草酮是从迷迭香中分离得到的一种二萜,是一种抗病毒和抗癌剂[1]。
• 相关类别:
  研究领域 >> 癌症
  研究领域 >> 感染
  信号通路 >> 其他 >> 其他
• 体外研究: 鼠尾草对SNU-1型人胃癌细胞有显著的细胞毒性作用[1]
• 参考文献:

  [1]. MASAHIRO TADA, et al. ANTIVIRAL DITERPENES FROM SAL VIA OFFZCZNALZS. Phytochemistry. Volume 35, Issue 2, January 1994, Pages 539-541.

  [2]. Sabina Shrestha, et al. Sageone, a diterpene from Rosmarinus officinalis, synergizes with cisplatin cytotoxicity in SNU-1 human gastric cancer cells. Phytomedicine. 2016 Dec 1;23(13):1671-1679.

紫苏酮物理化学性质

• 密度: 1.20±0.1 g/cm3
• 分子式: C₁₉H₂₄O₃
• 分子量: 300.39
• 精确质量: 300.17300
• PSA: 57.53000
• LogP: 4.31010
• InChIKey: NPQAMUFQEFLLCY-UHFFFAOYSA-N
• SMILES: CC(C)c1cc2c(c(O)c1O)C1=C(CC2)C(C)(C)CCC1=O
• 外观性状: 棕色粉末
• 储存条件: 2-8℃，干燥，密闭
• 水溶解性: Practically insoluble (0.015 g/L) (25 ºC)

紫苏酮安全信息

• 危害码 (欧洲): Xi

紫苏酮靶点实验

查看更多实验

实验名称：Antibiofilm activity against Pseudomonas aeruginosa ATCC 50071 assessed as inhibition... 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL4814885

实验名称：Antibiofilm activity against Staphylococcus aureus ATCC 25923 assessed as inhibition ... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4814886

实验名称：Antibiofilm activity against Listeria monocytogenes ATCC 7644 assessed as inhibition ... 来源：ChEMBL 靶标：Listeria monocytogenes External Id：CHEMBL4814884

实验名称：Antibiofilm activity against Escherichia coli DSM 8579 assessed as inhibition of bact... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL4814906

实验名称：Antibiofilm activity against Staphylococcus aureus ATCC 25923 assessed as inhibition ... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4814903

实验名称：Antibiofilm activity against Escherichia coli DSM 8579 assessed as inhibition of bact... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL4814907

实验名称：Activation of Nrf2/ARE in E15 stage mouse primary cortical neurons after 48 hrs by hu... 来源：ChEMBL 靶标：Nuclear factor erythroid 2-related factor 2 External Id：CHEMBL2379621

实验名称：Activation of Nrf2/ARE in E15 stage mouse primary cortical neurons at 6.25 to 50 uM a... 来源：ChEMBL 靶标：Nuclear factor erythroid 2-related factor 2 External Id：CHEMBL2379620

实验名称：Antibiofilm activity against Pseudomonas aeruginosa ATCC 50071 assessed as inhibition... 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL4814897

实验名称：Antibiofilm activity against Staphylococcus aureus ATCC 25923 assessed as inhibition ... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4814898

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紫苏酮英文别名

• 5,6-dihydroxy-7-isopropyl-1,1-dimethyl-2,3,9,10-tetrahydrophenanthren-4(1H)-one