1alpha-Hydroxy VD4

• 常用名: 1alpha-Hydroxy VD4
• 英文名: 1alpha-Hydroxy VD4
• CAS号: 143032-85-3
• 分子量: 414.66400
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₈H₄₆O₂
• 熔点: N/A
• 闪点: N/A

1alpha-Hydroxy VD4用途

1alpha-Hydroxy VD4是1alpha(OH)D的衍生物,能有效地诱导单核细胞性白血病细胞U937,P39/TSU和P31/FUJ的分化。

1alpha-Hydroxy VD4名称

• 中文名: 1alpha-Hydroxy VD4
• 英文名: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5S)-5,6-dimethylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

1alpha-Hydroxy VD4生物活性

• 描述: 1alpha-Hydroxy VD4是1alpha(OH)D的衍生物,能有效地诱导单核细胞性白血病细胞U937,P39/TSU和P31/FUJ的分化。
• 相关类别:
  信号通路 >> 维生素 D 相关 >> VD/VDR
  研究领域 >> 癌症
• 参考文献:

  [1]. M Makishima, et al. Growth inhibition and differentiation induction in human monoblastic leukaemia cells by 1alpha-hydroxyvitamin D derivatives and their enhancement by combination with hydroxyurea. British Journal of Cancer (1998) 77, 33-39

1alpha-Hydroxy VD4物理化学性质

• 分子式: C₂₈H₄₆O₂
• 分子量: 414.66400
• 精确质量: 414.35000
• PSA: 40.46000
• LogP: 6.83580
• InChIKey: NEETXMRNUNEBRH-UHFFFAOYSA-N
• SMILES: C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CCC(C)C(C)C)CC(O)CC1O
• 储存条件: 2-8℃

1alpha-Hydroxy VD4英文别名

• 1alpha-Hydroxy VD4
• CS-0805