醋酸西曲瑞克结构式
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常用名 | 醋酸西曲瑞克 | 英文名 | Cetrorelix Acetate |
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CAS号 | 145672-81-7 | 分子量 | 1491.09000 | |
密度 | N/A | 沸点 | N/A | |
分子式 | C72H96ClN17O16 | 熔点 | N/A | |
MSDS | 中文版 美版 | 闪点 | N/A | |
符号 |
GHS08 |
信号词 | Warning |
醋酸西曲瑞克用途Cetrorelix Acetate是 GnRH 受体的强效拮抗剂,其 IC50 值为 1.21 nM. |
中文名 | 醋酸西曲瑞克 |
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英文名 | cetrorelix acetate |
描述 | Cetrorelix Acetate是 GnRH 受体的强效拮抗剂,其 IC50 值为 1.21 nM. |
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相关类别 | |
靶点 |
IC50: 1.21 nM GnRH[1]. |
体外研究 | Cetrorelix Acetate以1000ng/ml抑制ES-2细胞系的生长。 Cetrorelix Acetate具有与GnRH-I激动剂相当的抗增殖作用,表明GnRH-I激动剂和拮抗剂的二分法可能不适用于癌细胞中的GnRH-I系统[2]。 |
参考文献 |
分子式 | C72H96ClN17O16 |
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分子量 | 1491.09000 |
精确质量 | 1489.69000 |
PSA | 532.97000 |
LogP | 6.02320 |
储存条件 | -20°C |
Successful fertility preservation following ovarian tissue vitrification in patients with primary ovarian insufficiency.
Hum. Reprod. 30(3) , 608-15, (2015) Is ovarian tissue cryopreservation using vitrification followed by in vitro activation (IVA) of dormant follicles a potential approach for infertility treatment of patients with primary ovarian insuff... |
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Ovarian stimulation and in-vitro fertilization outcomes of cancer patients undergoing fertility preservation compared to age matched controls: a 17-year experience.
J. Assist. Reprod. Genet. 32(4) , 587-96, (2015) To compare the in-vitro fertilization (IVF) outcomes of cancer patients who underwent oocyte retrieval and embryo/oocyte cryopreservation prior to gonadotoxic therapy to those of age and time-matched ... |
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Sperm morphological normality under high magnification predicts laboratory and clinical outcomes in couples undergoing ICSI.
Hum. Fertil. (Camb.) 18 , 81-6, (2015) The objective of this study was to evaluate whether 'motile sperm organelle morphology examination' (MSOME) is correlated with the outcome of ICSI. A total of 14400 spermatozoa from 72 couples undergo... |