1,7-双-(4-羟基苯基)-1,4,6-庚三烯-3-酮

• 常用名: 1,7-双-(4-羟基苯基)-1,4,6-庚三烯-3-酮
• 英文名: 1,7-Bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one
• CAS号: 149732-52-5
• 分子量: 292.33
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₁₆O₃
• 熔点: N/A
• 闪点: N/A

1,7-双-(4-羟基苯基)-1,4,6-庚三烯-3-酮用途

1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one 是一种有效的 N 蛋白抑制剂可以从 Curcuma kwangsiensis 中分离得到。1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one 对 HCoV-OC43 和 SARS-CoV-2 表现出优异的抗病毒活性,EC50 值分别为 0.16 μM 和 0.17 μM。

1,7-双-(4-羟基苯基)-1,4,6-庚三烯-3-酮名称

• 中文名: 1,7-双-(4-羟基苯基)-1,4,6-庚三烯-3-酮
• 英文名: 1,7-bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one

1,7-双-(4-羟基苯基)-1,4,6-庚三烯-3-酮生物活性

• 描述: 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one 是一种有效的 N 蛋白抑制剂可以从 Curcuma kwangsiensis 中分离得到。1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one 对 HCoV-OC43 和 SARS-CoV-2 表现出优异的抗病毒活性,EC50 值分别为 0.16 μM 和 0.17 μM。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> SARS冠状病毒
• 参考文献:

  [1]. Yang Liu, et al. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one inhibits SARS-CoV-2 by targeting the nucleocapsid protein. Acta Materia Medica. 2023. Vol. 2(3):270-280.

1,7-双-(4-羟基苯基)-1,4,6-庚三烯-3-酮物理化学性质

• 分子式: C₁₉H₁₆O₃
• 分子量: 292.33
• 精确质量: 292.11000
• PSA: 57.53000
• LogP: 3.94970
• InChIKey: PALMCMYYFAHUGA-BPTNNVFMSA-N
• SMILES: O=C(C=CC=Cc1ccc(O)cc1)C=Cc1ccc(O)cc1

1,7-双-(4-羟基苯基)-1,4,6-庚三烯-3-酮靶点实验

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