D-Epinephrine

• 常用名: D-Epinephrine
• 英文名: D-Epinephrine
• CAS号: 150-05-0
• 分子量: 183.20400
• 密度: 1.283g/cm3
• 沸点: 413.1ºC at 760mmHg
• 分子式: C₉H₁₃NO₃
• 熔点: N/A
• 闪点: 207.9ºC

D-Epinephrine用途

D-Epinephrine is a hormone, neurotransmitter, and medication. Epinephrine is normally produced by both the adrenal glands and certain neurons. It plays an important role in the fight-or-flight response by increasing blood flow to muscles, output of the heart, pupil dilation, and blood sugar. It does this by binding to alpha and beta receptors.

D-Epinephrine名称

• 英文名: (S)-adrenaline

D-Epinephrine物理化学性质

• 密度: 1.283g/cm3
• 沸点: 413.1ºC at 760mmHg
• 分子式: C₉H₁₃NO₃
• 分子量: 183.20400
• 闪点: 207.9ºC
• 精确质量: 183.09000
• PSA: 72.72000
• LogP: 0.74150
• InChIKey: UCTWMZQNUQWSLP-SECBINFHSA-N
• SMILES: CNCC(O)c1ccc(O)c(O)c1
• 蒸汽压: 1.45E-07mmHg at 25°C
• 折射率: 1.607
• 储存条件:

  通风低温干燥处。

• 稳定性:

  受热较易燃; 燃烧释放有毒氮氧化物烟雾; 药物副作用: 接触皮炎,短期内可消失。

• 分子结构:

  1、 摩尔折射率：49.33

  2、 摩尔体积（cm³/mol）：142.6

  3、 等张比容（90.2K）：397.0

  4、 表面张力（dyne/cm）：59.9

  5、 极化率（10-24cm3）：19.55

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:4

  3.氢键受体数量:4

  4.可旋转化学键数量:3

  5.互变异构体数量:10

  6.拓扑分子极性表面积72.7

  7.重原子数量:13

  8.表面电荷:0

  9.复杂度:154

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:1

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

D-Epinephrine毒性和生态

D-Epinephrine毒理学数据:

静脉-大鼠 LD50: 0.8 毫克/公斤；静脉-小鼠 LD50：38 毫克/公斤。

D-Epinephrine靶点实验

查看更多实验

实验名称：Activation of human recombinant CA3 at 10 uM by stopped-flow CO2 hydration method 来源：ChEMBL 靶标：Carbonic anhydrase 3 External Id：CHEMBL970752

实验名称：Activation of human recombinant CA2 at 10 uM by stopped-flow CO2 hydration method 来源：ChEMBL 靶标：Carbonic anhydrase 2 External Id：CHEMBL970751

实验名称：Activation of human recombinant truncated CA4 at 10 uM by stopped-flow CO2 hydration ... 来源：ChEMBL 靶标：Carbonic anhydrase 4 External Id：CHEMBL970753

实验名称：Activation of human recombinant CA1 by stopped-flow CO2 hydration method 来源：ChEMBL 靶标：Carbonic anhydrase 1 External Id：CHEMBL932481

实验名称：Activation of human recombinant CA1 at 10 uM by stopped-flow CO2 hydration method 来源：ChEMBL 靶标：Carbonic anhydrase 1 External Id：CHEMBL970750

实验名称：Binding of [3H]dihydroalprenolol to beta-2 adrenergic receptor of rat cerebral cortic... 来源：ChEMBL 靶标：Beta-2 adrenergic receptor External Id：CHEMBL652293

实验名称：Activity of Sulfurihydrogenibium yellowstonense YO3AOP1 recombinant CA expressed in E... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2156562

实验名称：Activation of human recombinant CA2 by stopped-flow CO2 hydration method 来源：ChEMBL 靶标：Carbonic anhydrase 2 External Id：CHEMBL932482

实验名称：Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in H... 来源：Southern Research Institute 靶标：CFTR External Id：CF Folding

实验名称：Activation of human recombinant CA9 catalytic domain by stopped-flow CO2 hydration me... 来源：ChEMBL 靶标：Carbonic anhydrase 9 External Id：CHEMBL932483

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D-Epinephrine英文别名

• EINECS 205-752-5
• (+)-epinephrine
• 4-[(1S)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
• (3,4-dihydroxyphenyl)-1-hydroxy-2-methylaminoethan