盐酸替罗非班

更新时间：2025-08-22 22:30:50

盐酸替罗非班结构式	常用名	盐酸替罗非班	英文名	Tirofiban hydrochloride
	CAS号	150915-40-5	分子量	495.073
	密度	N/A	沸点	611.7ºC at 760 mmHg
	分子式	C₂₂H₃₉ClN₂O₆S	熔点	135-137ºC
	MSDS	中文版美版	闪点	323.7ºC
	符号	GHS07	信号词	Warning

盐酸替罗非班用途

Tirofiban盐酸盐一水合物是非肽类,糖蛋白IIb/IIIa拮抗剂。

中文名	盐酸替罗非班
英文名	tirofiban hydrochloride
中文别名	替罗非班盐酸盐水合物 \| N-(正丁基磺酰基)-O-[4-(4-哌啶基)丁基]-L-酪氨酸盐酸盐水合物 \| 盐酸替罗非班
英文别名	更多

描述	Tirofiban盐酸盐一水合物是非肽类,糖蛋白IIb/IIIa拮抗剂。
相关类别	信号通路 >> 细胞骨架 >> Integrin 研究领域 >> 心血管疾病
参考文献	[1]. Winter JP, Juergens CP. The role of tirofiban in the management of coronary artery disease. Cardiovasc Hematol Disord Drug Targets. 2008 Jun;8(2):138-46. [2]. van 't Hof AW, Valgimigli M. Defining the role of platelet glycoprotein receptor inhibitors in STEMI: focus on tirofiban. Drugs. 2009;69(1):85-100. [3]. Valgimigli M, Biondi-Zoccai G, Tebaldi M et al. Tirofiban as adjunctive therapy for acute coronary syndromes and percutaneous coronary intervention: a meta-analysis of randomized trials. Eur Heart J. 2010 Jan;31(1):35-49. [4]. Valgimigli M, Tebaldi M. Safety evaluation of tirofiban. Expert Opin Drug Saf. 2010 Sep;9(5):801-19. [5]. Diaz JF, Cardenal R, Gomez-Manchero A, Sanchez-Gonzalez C. Safety and efficacy of tirofiban as adjunctive therapy for patients with ST-elevation myocardial infarction: a comparison versus placebo and abciximab. Cardiovasc Hematol Agents Med Chem. 2011 Jul 1;9(3):147-53.

描述

Tirofiban盐酸盐一水合物是非肽类,糖蛋白IIb/IIIa拮抗剂。

相关类别

信号通路 >> 细胞骨架 >> Integrin

研究领域 >> 心血管疾病

参考文献

[1]. Winter JP, Juergens CP. The role of tirofiban in the management of coronary artery disease. Cardiovasc Hematol Disord Drug Targets. 2008 Jun;8(2):138-46.

[2]. van 't Hof AW, Valgimigli M. Defining the role of platelet glycoprotein receptor inhibitors in STEMI: focus on tirofiban. Drugs. 2009;69(1):85-100.

[3]. Valgimigli M, Biondi-Zoccai G, Tebaldi M et al. Tirofiban as adjunctive therapy for acute coronary syndromes and percutaneous coronary intervention: a meta-analysis of randomized trials. Eur Heart J. 2010 Jan;31(1):35-49.

[4]. Valgimigli M, Tebaldi M. Safety evaluation of tirofiban. Expert Opin Drug Saf. 2010 Sep;9(5):801-19.

[5]. Diaz JF, Cardenal R, Gomez-Manchero A, Sanchez-Gonzalez C. Safety and efficacy of tirofiban as adjunctive therapy for patients with ST-elevation myocardial infarction: a comparison versus placebo and abciximab. Cardiovasc Hematol Agents Med Chem. 2011 Jul 1;9(3):147-53.

沸点	611.7ºC at 760 mmHg
熔点	135-137ºC
分子式	C₂₂H₃₉ClN₂O₆S
分子量	495.073
闪点	323.7ºC
精确质量	494.221741
PSA	122.34000
LogP	5.48870
外观性状	白色固体
储存条件	-20°C Freezer
水溶解性	DMSO: >12mg/mL at warmed to 60°C

符号	GHS07
信号词	Warning
危害声明	H315-H319-H335
警示性声明	P261-P305 + P351 + P338
危害码 (欧洲)	Xi
风险声明 (欧洲)	36/37/38
安全声明 (欧洲)	26-37-45
危险品运输编码	NONH for all modes of transport

Influence of Body Mass Index on the Activated Clotting Time Under Weight-Based Heparin Dose.

J. Clin. Lab Anal. 30 , 108-13, (2016)

Activated clotting time (ACT) has been successfully applied during percutaneous coronary intervention (PCI) to monitor the extent of thrombin inhibition and anti-coagulation from unfractionated hepari...

L 700462 MK 383 N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine

N-(butylsulfonyl)- O-[4-(4-piperidinyl)butyl]-L-tyrosine monohydrochloride monohydrate

N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]tyrosine hydrochloride hydrate

N-(Butylsulfonyl)-O-[4-(piperidin-4-yl)butyl]-L-tyrosine hydrochloride hydrate

(2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid,hydrate,hydrochloride

Tirofiban hydrochloride

Tirofiban hydrochloride monohydrate

tirofiban hydrochloride anhydrous

Tyrosine, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-, hydrochloride, hydrate (1:1:1)

Tirofiban Hydrochloride Hydrate

Tirofiban (hydrochloride monohydrate)