N-Phenylsulfamide

• 常用名: N-Phenylsulfamide
• 英文名: N-Phenylsulfamide
• CAS号: 15959-53-2
• 分子量: 172.20500
• 密度: N/A
• 沸点: N/A
• 分子式: C₆H₈N₂O₂S
• 熔点: N/A
• 闪点: N/A

N-Phenylsulfamide用途

苯磺胺(化合物10)是一种人体碳酸酐酶II(hCA II)抑制剂,其Kd为45.50μM,Ki为79.60μM[1]。

N-Phenylsulfamide名称

• 英文名: (sulfamoylamino)benzene

N-Phenylsulfamide生物活性

• 描述: 苯磺胺(化合物10)是一种人体碳酸酐酶II(hCA II)抑制剂,其Kd为45.50μM,Ki为79.60μM[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 代谢酶/蛋白酶 >> 碳酸酐酶
• 靶点实验:

  hCA II:45.50 μM (Kd)

  hCA II:79.60 μM (Ki)

• 参考文献:

  [1]. Klinger AL, et al. Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements. J Med Chem. 2006 Jun 15;49(12):3496-500.

N-Phenylsulfamide物理化学性质

• 分子式: C₆H₈N₂O₂S
• 分子量: 172.20500
• 精确质量: 172.03100
• PSA: 80.57000
• LogP: 2.15610
• InChIKey: DEVUYWTZRXOMSI-UHFFFAOYSA-N
• SMILES: NS(=O)(=O)Nc1ccccc1

N-Phenylsulfamide靶点实验

查看更多实验

实验名称：Inhibitory activity against human cloned isoenzyme carbonic anhydrase II (hCA II), by... 来源：ChEMBL 靶标：Carbonic anhydrase 2 External Id：CHEMBL658045

实验名称：Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to ... 来源：ChEMBL 靶标：Carbonic anhydrase 2 External Id：CHEMBL2049249

实验名称：Inhibitory activity against human cloned isoenzyme carbonic anhydrase I (hCA I), by e... 来源：ChEMBL 靶标：Carbonic anhydrase 1 External Id：CHEMBL662727

实验名称：Inhibition of GST-tagged Malassezia globosa ATCC 96807/CBS 7966 MG-CA expressed in Es... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2049253

实验名称：Inhibition of Cryptococcus neoformans Can2 preincubated for 15 mins measured for 10 t... 来源：ChEMBL 靶标：Carbonic anhydrase External Id：CHEMBL2049250

实验名称：Inhibition of Candida albicans CaNce103 preincubated for 15 mins measured for 10 to 1... 来源：ChEMBL 靶标：Carbonic anhydrase External Id：CHEMBL2049251

实验名称：Binding affinity to human CA2 by ThermoFluor assay 来源：ChEMBL 靶标：Carbonic anhydrase 2 External Id：CHEMBL854244

实验名称：Inhibition of human CA2 by carbon dioxide hydration 来源：ChEMBL 靶标：Carbonic anhydrase 2 External Id：CHEMBL854245

共8条，当前第1页，共1页

1

N-Phenylsulfamide英文别名

• aniline sulfonic acid amide
• Phenyl-sulfamid
• 4-sulfamoylaminobenzene
• sulfamoylphenylamide
• phenylsulfamide
• Schwefelsaeure-amid-anilid
• N-phenyl sulfamide
• Sulfamide,phenyl