N-Phenylsulfamide

Modify Date: 2024-01-09 08:23:46

N-Phenylsulfamide Structure
N-Phenylsulfamide structure
Common Name N-Phenylsulfamide
CAS Number 15959-53-2 Molecular Weight 172.20500
Density N/A Boiling Point N/A
Molecular Formula C6H8N2O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Phenylsulfamide


Phenylsulfamide (Compound 10) is a human carbonic anhydrase-II (hCA-II) inhibitor with a Kd of 45.50 μM and a Ki of 79.60 μM[1].

 Names

Name (sulfamoylamino)benzene
Synonym More Synonyms

 N-Phenylsulfamide Biological Activity

Description Phenylsulfamide (Compound 10) is a human carbonic anhydrase-II (hCA-II) inhibitor with a Kd of 45.50 μM and a Ki of 79.60 μM[1].
Related Catalog
Target

hCA II:45.50 μM (Kd)

hCA II:79.60 μM (Ki)

References

[1]. Klinger AL, et al. Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements. J Med Chem. 2006 Jun 15;49(12):3496-500.

 Chemical & Physical Properties

Molecular Formula C6H8N2O2S
Molecular Weight 172.20500
Exact Mass 172.03100
PSA 80.57000
LogP 2.15610

 Synthetic Route

 Synonyms

aniline sulfonic acid amide
Phenyl-sulfamid
4-sulfamoylaminobenzene
sulfamoylphenylamide
phenylsulfamide
Schwefelsaeure-amid-anilid
N-phenyl sulfamide
Sulfamide,phenyl