Nav1.8-IN-4

• 常用名: Nav1.8-IN-4
• 英文名: Nav1.8-IN-4
• CAS号: 1620846-16-3
• 分子量: 406.33
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₄F₄N₂O₃
• 熔点: N/A
• 闪点: N/A

Nav1.8-IN-4用途

Nav1.8-IN-4 (化合物 9a) 是一种 Nav1.8 通道抑制剂 (IC50=0.014 μM)。Nav1.8-IN-4 可用于疼痛相关疾病的研究。

Nav1.8-IN-4名称

• 英文名: Nav1.8-IN-4

Nav1.8-IN-4生物活性

• 描述: Nav1.8-IN-4 (化合物 9a) 是一种 Nav1.8 通道抑制剂 (IC50=0.014 μM)。Nav1.8-IN-4 可用于疼痛相关疾病的研究。
• 相关类别:
  信号通路 >> 跨膜转运 >> 钠通道
  研究领域 >> 感染
• 靶点实验:

  IC50=0.014 μM (Nav1.8)[1].

• 参考文献:

  [1]. Corey Anderson, et al. Prodrugs of pyridone amides useful as modulators of sodium channels. Patent WO2015089361A1.

Nav1.8-IN-4物理化学性质

• 分子式: C₂₀H₁₄F₄N₂O₃
• 分子量: 406.33
• 储存条件: -20℃

Nav1.8-IN-4靶点实验

查看更多实验

实验名称：Analgesic activity in CFA-induced inflammatory pain mouse model assessed as increase ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5585809

实验名称：Analgesic activity in CFA-induced inflammatory pain mouse model assessed as increase ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5585812

实验名称：Selectivity ratio of binding affinity to Nav1.8 (unknown origin) expressed in HEK293T... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5389102

实验名称：Binding affinity to Nav1.5 (unknown origin) expressed in HEK293T cells assessed as re... 来源：ChEMBL 靶标：Sodium channel protein type 5 subunit alpha External Id：CHEMBL5389101

实验名称：Binding affinity to Nav1.8 (unknown origin) expressed in HEK293T cells assessed as re... 来源：ChEMBL 靶标：Sodium channel protein type 10 subunit alpha External Id：CHEMBL5389100

实验名称：Binding affinity to Nav1.8 (unknown origin) expressed in HEK293 cells assessed as ret... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5585806

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