Sutezolid

• 常用名: Sutezolid
• 英文名: Sutezolid
• CAS号: 168828-58-8
• 分子量: 353.41200
• 密度: 1.321g/cm3
• 沸点: 609ºC at 760 mmHg
• 分子式: C₁₆H₂₀FN₃O₃S
• 熔点: N/A
• 闪点: 322.1ºC
• 符号: GHS07
• 信号词: Warning

Sutezolid用途

Sutezolid(PNU-100480)是一种恶唑烷酮类抗菌剂,用于治疗结核病。

Sutezolid名称

• 中文名: Sutezolid
• 英文名: N-[[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

Sutezolid生物活性

• 描述: Sutezolid(PNU-100480)是一种恶唑烷酮类抗菌剂,用于治疗结核病。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 感染
• 参考文献:

  [1]. Zhu T, et al. Population pharmacokinetic/pharmacodynamic analysis of the bactericidal activities of sutezolid (PNU-100480) and its major metabolite against intracellular Mycobacterium tuberculosis in ex vivo whole-blood cultures ofpatients with pulmonary

  [2]. Wallis RS, et al. Mycobactericidal activity of sutezolid (PNU-100480) in sputum (EBA) and blood (WBA) of patients with pulmonary tuberculosis. PLoS One. 2014 Apr 14;9(4):e94462.

Sutezolid物理化学性质

• 密度: 1.321g/cm3
• 沸点: 609ºC at 760 mmHg
• 分子式: C₁₆H₂₀FN₃O₃S
• 分子量: 353.41200
• 闪点: 322.1ºC
• 精确质量: 353.12100
• PSA: 87.18000
• LogP: 2.36110
• InChIKey: FNDDDNOJWPQCBZ-ZDUSSCGKSA-N
• SMILES: CC(=O)NCC1CN(c2ccc(N3CCSCC3)c(F)c2)C(=O)O1
• 蒸汽压: 8.97E-15mmHg at 25°C
• 折射率: 1.584
• 储存条件: 2-8℃

Sutezolid安全信息

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 危险品运输编码: NONH for all modes of transport

Sutezolid靶点实验

查看更多实验

实验名称：Compound was evaluated for in vitro anti-mycobacterial activity against Mycobacterium... 来源：ChEMBL 靶标：Mycobacterium avium External Id：CHEMBL745310

实验名称：Compound was evaluated for in vitro anti-mycobacterial activity against Mycobacterium... 来源：ChEMBL 靶标：Mycobacterium avium External Id：CHEMBL745311

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：In vitro anti-mycobacterial activity against Mycobacterium smegmatis determined by th... 来源：ChEMBL 靶标：Mycobacterium External Id：CHEMBL745308

实验名称：In vitro anti-mycobacterial activity against streptomycin resistant Mycobacterium tub... 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL749509

实验名称：Compound was evaluated for in vitro anti-mycobacterial activity against Mycobacterium... 来源：ChEMBL 靶标：Mycobacterium avium External Id：CHEMBL745309

实验名称：In vitro anti-mycobacterial activity against Mycobacterium tuberculosis ATCC 27294, d... 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL749515

实验名称：In vitro anti-mycobacterial activity against Mycobacterium tuberculosis C.I. 1104, de... 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL749516

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020);... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4296184

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Sutezolid英文别名

• (S)-N-[[3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide
• N[[(5S)-3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
• Sutezolid [USAN]
• N-{[3-(3-Fluoro-4-(1,4-thiazaperhydroin-4-yl)phenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
• Sutezolid
• Sutezolid [INN]