(S)-Lercanidipine hydrochloride

• 常用名: (S)-Lercanidipine hydrochloride
• 英文名: (S)-Lercanidipine HCl
• CAS号: 184866-29-3
• 分子量: 648.188
• 密度: N/A
• 沸点: 712.5ºC at 760 mmHg
• 分子式: C₃₆H₄₂ClN₃O₆
• 熔点: 116-122ºC
• 闪点: 384.7ºC

(S)-Lercanidipine hydrochloride用途

(S)-Lercanidipine hydrochloride 是 Lercanidipine hydrochloride 的 S- 对映体。(S)-lercanidipine hydrochloride 是一个高效的钙离子通道阻断剂。

(S)-Lercanidipine hydrochloride名称

• 中文名: (S)-盐酸乐卡地平
• 英文名: 5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate,hydrochloride

(S)-Lercanidipine hydrochloride生物活性

• 描述: (S)-Lercanidipine hydrochloride 是 Lercanidipine hydrochloride 的 S- 对映体。(S)-lercanidipine hydrochloride 是一个高效的钙离子通道阻断剂。
• 相关类别:
  信号通路 >> 跨膜转运 >> 钙通道
  研究领域 >> 心血管疾病
• 参考文献:

  [1]. Wirtz S,et al. Molecular mechanisms of vasoselectivity of the 1,4-dihydropyridine lercanidipine. Br J Pharmacol. 2004 May;142(2):275-84.

(S)-Lercanidipine hydrochloride物理化学性质

• 沸点: 712.5ºC at 760 mmHg
• 熔点: 116-122ºC
• 分子式: C₃₆H₄₂ClN₃O₆
• 分子量: 648.188
• 闪点: 384.7ºC
• 精确质量: 647.276184
• PSA: 113.69000
• LogP: 8.13240
• 蒸汽压: 3.77E-20mmHg at 25°C

(S)-Lercanidipine hydrochloride英文别名

• 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methyl-2-propanyl methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate hydrochloride (1:1)
• (4S)-1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester Hydrochloride
• UNII-OA8TFX68PE component WMFYOYKPJLRMJI-WAQYZQTGSA-N
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester, (4S)-, hydrochloride (1:1)
• (S)-Lercanidipine Hydrochloride