泰利霉素

• 常用名: 泰利霉素
• 英文名: Telithromycin
• CAS号: 191114-48-4
• 分子量: 812.004
• 密度: 1.3±0.1 g/cm3
• 沸点: 966.2±65.0 °C at 760 mmHg
• 分子式: C₄₃H₆₅N₅O₁₀
• 熔点: 176-188ºC
• 闪点: 538.2±34.3 °C

泰利霉素用途

Telithromycin(HMR3647)为可作用于社区获得性肺炎的抗生素。

泰利霉素名称

• 中文名: 泰利霉素
• 英文名: Telithromycin
• 中文别名: 红霉酮(特利霉素)

泰利霉素生物活性

• 描述: Telithromycin(HMR3647)为可作用于社区获得性肺炎的抗生素。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 感染
• 参考文献:

  [1]. http://en.wikipedia.org/wiki/Telithromycin

泰利霉素物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 966.2±65.0 °C at 760 mmHg
• 熔点: 176-188ºC
• 分子式: C₄₃H₆₅N₅O₁₀
• 分子量: 812.004
• 闪点: 538.2±34.3 °C
• 精确质量: 811.473145
• PSA: 171.85000
• LogP: 4.52
• InChIKey: LJVAJPDWBABPEJ-HKEYBQESSA-N
• SMILES: CCC1OC(=O)C(C)C(=O)C(C)C(OC2OC(C)CC(N(C)C)C2O)C(C)(OC)CC(C)C(=O)C(C)C2N(CCCCn3cnc(-c4cccnc4)c3)C(=O)OC12C
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.589
• 储存条件: -20?C Freezer

泰利霉素安全信息

• 危害码 (欧洲): Xi
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): 26-36

泰利霉素靶点实验

查看更多实验

实验名称：Ratio of MBC to MIC against azithromycin-susceptible Haemophilus influenzae ATCC 4924... 来源：ChEMBL 靶标：Haemophilus influenzae External Id：CHEMBL4007185

实验名称：Bactericidal activity against azithromycin-susceptible Haemophilus influenzae ATCC 49... 来源：ChEMBL 靶标：Haemophilus influenzae External Id：CHEMBL4007184

实验名称：Antibacterial activity against macrolide-susceptible Staphylococcus aureus Smith infe... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL1012865

实验名称：Antibacterial activity against macrolide-resistant Staphylococcus aureus 7701 infecte... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL1012866

实验名称：Antibacterial activity against macrolide-susceptible Staphylococcus aureus Smith by b... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL1012867

实验名称：Antimicrobial activity against doxycyclin-resistant Orientia tsutsugamushi in patient... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL938264

实验名称：Antibacterial activity against Enterococcus faecalis 29212 by broth microdilution met... 来源：ChEMBL 靶标：Enterococcus faecalis External Id：CHEMBL856340

实验名称：Antibacterial activity against Enterococcus faecalis bc11148-2 by broth microdilution... 来源：ChEMBL 靶标：Enterococcus faecalis External Id：CHEMBL856341

实验名称：Antibacterial activity against Streptococcus pyogenes 8668 by broth microdilution met... 来源：ChEMBL 靶标：Streptococcus pyogenes External Id：CHEMBL856342

实验名称：Antibacterial activity against Streptococcus pneumoniae 49619 by broth microdilution ... 来源：ChEMBL 靶标：Streptococcus pneumoniae External Id：CHEMBL856948

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泰利霉素英文别名

• KETEK
• (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxo-1-[4-(4-pyridin-3-yl-1H-imidazol-1-yl)butyl]tetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside
• (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-10-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-1-[4-(4-pyridin-3-yl-1H-imidazol-1-yl)butyl]octahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-2,6,8,14(1H,7H,9H)-tetron
• (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-Ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxo-1-{4-[4-(3-pyridinyl)-1H-imidazol-1-yl]butyl}tetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol ;-10-yl 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside
• Telithromycin
• (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-Ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxo-1-{4-[4-(pyridin-3-yl)-1H-imidazol-1-yl]butyl}tetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside
• (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-10-{[(2S,3R,4S,6R)-4-(diméthylamino)-3-hydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}-4-éthyl-11-méthoxy-3a,7,9,11,13,15-hexaméthyl-1-[4-(4-pyridin-3-yl-1H-imidazol-1-yl)butyl]octahydro-2H-oxacyclotétradécino[4,3-d][1,3]oxazole-2,6,8,14(1H,7H,9H)-tétrone
• (1R,2R,4R,6S,7R,8R,10R,13R,14S)-7-[(2S,3R,4S,6R)-4-Dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-13-ethyl-6-methoxy-2,4,6,8,10,14-hexamethyl-17-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-12,15-dioxa-17-azabicyclo[12.3.0]heptadecane-3,9,11,16-tetrone
• (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-10-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-1-[4-(4-pyridin-3-yl-1H-imidazol-1-yl)butyl]octahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazole-2,6,8,14(1H,7H,9H)-tetrone
• MFCD04117983
• 3-De((2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy)-11,12-dideoxy-6-O-methyl-3-oxo-12,11-(oxycarbonyl((4-(4-(3-pyridinyl)-1H-imidazol-1-yl)butyl)imino))erythromycin