PF-06463922 acetate

• 常用名: PF-06463922 acetate
• 英文名: PF-06463922 acetate
• CAS号: 1924207-18-0
• 分子量: 466.465
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₃FN₆O₄
• 熔点: N/A
• 闪点: N/A

PF-06463922 acetate用途

PF-06463922 acetate is a potent, selective brain-penetrable inhibitor of both anaplastic lymphoma kinase (ALK) and c-ros Oncogene 1 (ROS1) with strong activity against all known ALK and ROS1 mutants identified in patients with crizotinib-resistant disease. PF-06463922 is in clinical trials for the treatment of non–small cell lung cancer (NSCLC).

PF-06463922 acetate名称

• 英文名: Lorlatinib acetate

PF-06463922 acetate物理化学性质

• 分子式: C₂₃H₂₃FN₆O₄
• 分子量: 466.465
• 精确质量: 466.176483

PF-06463922 acetate英文别名

• Lorlatinib acetate
• (16R)-19-Amino-13-fluoro-4,8,16-trimethyl-9-oxo-17-oxa-4,5,8,20-tetraazatetracyclo[16.3.1.02,6.010,15]docosa-1(22),2,5,10,12,14,18,20-octaene-3-carbonitrile acetate (1:1)
• (10R).7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H.8,4-(metheno)pyrazolo[4,3.h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile acetate
• PF-06463922 acetate
• 2H-8,4-Methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile, 7-amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-, (10R)-, acetate (1:1)