培西洛星

• 常用名: 培西洛星
• 英文名: 2-Pyrrolidinone,1-[(2E,4E,6E,8R)-8-hydroxy-6-methyl-1-oxo-2,4,6-dodecatrien-1-yl]
• CAS号: 19504-77-9
• 分子量: 291.39
• 密度: 1.088g/cm3
• 沸点: 481.2ºC at 760mmHg
• 分子式: C₁₇H₂₅NO₃
• 熔点: N/A
• 闪点: 244.8ºC

培西洛星用途

Variotin 是一种抗真菌 (Fungal) 剂。Variotin 对毛癣菌、小孢癣菌、表皮癣菌等皮肤癣菌,以及芽生菌、隐球菌等内部真菌病的致病真菌有较强的抗菌活性。

培西洛星名称

• 中文名: 培西洛星
• 英文名: 1-[(2E,4E,6E,8R)-8-hydroxy-6-methyldodeca-2,4,6-trienoyl]pyrrolidin-2-one

培西洛星生物活性

• 描述: Variotin 是一种抗真菌 (Fungal) 剂。Variotin 对毛癣菌、小孢癣菌、表皮癣菌等皮肤癣菌,以及芽生菌、隐球菌等内部真菌病的致病真菌有较强的抗菌活性。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 真菌
• 参考文献:

  [1]. MATSUDA A, et al. Studies on antifungal activity of variotin. J Antibiot (Tokyo). 1959 Sep;12:203-9.

培西洛星物理化学性质

• 密度: 1.088g/cm3
• 沸点: 481.2ºC at 760mmHg
• 分子式: C₁₇H₂₅NO₃
• 分子量: 291.39
• 闪点: 244.8ºC
• 精确质量: 291.18300
• PSA: 57.61000
• LogP: 2.68310
• InChIKey: ZYPGADGCNXOUJP-CXVPHVKISA-N
• SMILES: CCCCC(O)C=C(C)C=CC=CC(=O)N1CCCC1=O
• 蒸汽压: 2.79E-11mmHg at 25°C
• 折射率: 1.538

培西洛星毒性和生态

培西洛星靶点实验

查看更多实验

实验名称：Inhibition of mouse DNA polymerase lambda assessed as inhibition of incorporation of ... 来源：ChEMBL 靶标：DNA polymerase lambda External Id：CHEMBL3132086

实验名称：Inhibition of bovine deoxyribonuclease 1 assessed as inhibition of incorporation of d... 来源：ChEMBL 靶标：Deoxyribonuclease-1 External Id：CHEMBL3132087

实验名称：Inhibition of T4 bacteriophage polynucleotide kinase assessed as inhibition of incorp... 来源：ChEMBL 靶标：Polynucleotide kinase External Id：CHEMBL3132088

实验名称：USP8 deubiquitinase inhibition: Primary qHTS 来源：24642 靶标：ubiquitin specific peptidase 8 External Id：USP8 FAST DUB HTS Primary

实验名称：Inhibition of mouse IMP dehydrogenase 2 assessed as inhibition of incorporation of dT... 来源：ChEMBL 靶标：Inosine-5'-monophosphate dehydrogenase 2 External Id：CHEMBL3132089

实验名称：Inhibition of T7 RNA polymerase assessed as inhibition of incorporation of dTTP into ... 来源：ChEMBL 靶标：T7 RNA polymerase External Id：CHEMBL3132090

实验名称：USP17 deubiquitinase inhibition: Primary qHTS 来源：24642 靶标：ubiquitin specific peptidase 17 like family member 5 External Id：USP17 FAST DUB HTS Primary

实验名称：Inhibition of calf DNA primase of polymerase alpha assessed as inhibition of incorpor... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3132091

实验名称：USP7 deubiquitinase inhibition: Primary qHTS 来源：24642 靶标：ubiquitin specific peptidase 7 External Id：USP7 FAST DUB HTS Primary

实验名称：Inhibition of HIV-1 reverse transcriptase assessed as inhibition of incorporation of ... 来源：ChEMBL 靶标：Reverse transcriptase/RNaseH External Id：CHEMBL3132092

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培西洛星英文别名

• Leofungine
• Supral
• EINECS 243-116-9
• Pecilocin
• variotin