氯甲烯土霉素

• 常用名: 氯甲烯土霉素
• 英文名: GS-2989
• CAS号: 2013-58-3
• 分子量: 476.86
• 密度: 1.72g/cm3
• 沸点: 716.4ºC at 760mmHg
• 分子式: C₂₂H₂₁ClN₂O₈
• 熔点: N/A
• 闪点: 387.1ºC

氯甲烯土霉素用途

Meclocycline 是一种四环素衍生物。四环素的主要靶标是细菌核糖体。

氯甲烯土霉素名称

• 中文名: 氯甲烯土霉素
• 英文名: meclocycline
• 中文别名: 甲氯环素

氯甲烯土霉素生物活性

• 描述: Meclocycline 是一种四环素衍生物。四环素的主要靶标是细菌核糖体。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Fuoco D. Cytotoxicity induced by tetracyclines via protein photooxidation[J]. Advances in Toxicology, et al. Cytotoxicity induced by tetracyclines via protein photooxidation[J]. Advances in Toxicology, 2015, 2015.

氯甲烯土霉素物理化学性质

• 密度: 1.72g/cm3
• 沸点: 716.4ºC at 760mmHg
• 分子式: C₂₂H₂₁ClN₂O₈
• 分子量: 476.86
• 闪点: 387.1ºC
• 精确质量: 476.09900
• PSA: 181.62000
• LogP: 0.91580
• 蒸汽压: 0mmHg at 25°C

氯甲烯土霉素毒性和生态

氯甲烯土霉素靶点实验

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实验名称：Binding affinity towards rat Gabra1 in an in vitro assay with cellular components mea... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit alpha-1 External Id：CHEMBL5291800

实验名称：Binding affinity towards human ADRA2A in an in vitro assay with cellular components m... 来源：ChEMBL 靶标：Alpha-2A adrenergic receptor External Id：CHEMBL5291736

实验名称：Binding affinity towards human PGR in an in vitro assay with cellular components meas... 来源：ChEMBL 靶标：Progesterone receptor External Id：CHEMBL5291863

实验名称：Binding affinity to biotinylated pre-miRNA-21 (unknown origin) by SPR analysis 来源：ChEMBL 靶标：microRNA 21 External Id：CHEMBL4364424

实验名称：Antagonist activity at human ADRA1A in an in vitro cell-based assay measured by fluor... 来源：ChEMBL 靶标：Alpha-1A adrenergic receptor External Id：CHEMBL5291731

实验名称：Binding affinity towards human ESR1 in an in vitro cell free assay (CRO assay) measur... 来源：ChEMBL 靶标：Estrogen receptor External Id：CHEMBL5291792

实验名称：Binding affinity towards human ADORA3 (agonistic activity) in an in vitro assay with ... 来源：ChEMBL 靶标：Adenosine receptor A3 External Id：CHEMBL5291728

实验名称：Compound was evaluated for inhibition of human PDE3A in an in vitro cell free assay m... 来源：ChEMBL 靶标：cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A External Id：CHEMBL5291856

实验名称：Binding affinity towards human OPRM1 in an in vitro assay with cellular components me... 来源：ChEMBL 靶标：Mu-type opioid receptor External Id：CHEMBL5291855

实验名称：Agonist activity at human ADRA1A in an in vitro cell-based assay (CRO assay) measured... 来源：ChEMBL 靶标：Alpha-1A adrenergic receptor External Id：CHEMBL5291730

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氯甲烯土霉素英文别名

• meclocyline
• Meclocycline(usan)
• GS-2989
• Meclocycline base
• Chlormethylenecycline