6-Alpha Naloxol

• 常用名: 6-Alpha Naloxol
• 英文名: 6-Alpha Naloxol
• CAS号: 20410-95-1
• 分子量: 329.39000
• 密度: 1.43g/cm3
• 沸点: 532.5ºC at 760mmHg
• 分子式: C₁₉H₂₃NO₄
• 熔点: N/A
• 闪点: 275.8ºC

6-Alpha Naloxol用途

6-Alpha Naloxol(Alpha-Naloxol)是opioid拮抗剂，naloxone的代谢物。

6-Alpha Naloxol名称

• 中文名: 6α-纳洛索
• 英文名: 6 α-naloxol

6-Alpha Naloxol生物活性

• 描述: 6-Alpha Naloxol(Alpha-Naloxol)是opioid拮抗剂,naloxone的代谢物。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 阿片受体
  信号通路 >> 神经信号通路 >> 阿片受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Weinstein SH, et al. Metabolites of naloxone in human urine. J Pharm Sci. 1971 Oct;60(10):1567-8.

  [2]. Csaba Simon, et al. Stereoselective synthesis of β-naltrexol, β-naloxol β-naloxamine, β-naltrexamine and related compounds by the application of the mitsunobu reac. Tetrahedron Volume 50, Issue 32, 1994, Pages 9757–9768.

  [3]. Schulteis G, et al. Relative potency of the opioid antagonists naloxone and 6-alpha-naloxol to precipitate withdrawal from acute morphine dependence varies with time post-antagonist. Pharmacol Biochem Behav. 2009 Mar;92(1):157-63.

6-Alpha Naloxol物理化学性质

• 密度: 1.43g/cm3
• 沸点: 532.5ºC at 760mmHg
• 分子式: C₁₉H₂₃NO₄
• 分子量: 329.39000
• 闪点: 275.8ºC
• 精确质量: 329.16300
• PSA: 73.16000
• LogP: 1.03110
• InChIKey: HMWHERQFMBEHNG-AQQQZIQISA-N
• SMILES: C=CCN1CCC23c4c5ccc(O)c4OC2C(O)CCC3(O)C1C5
• 蒸汽压: 3.62E-12mmHg at 25°C
• 折射率: 1.701
• 储存条件: -20°C，密闭，干燥

6-Alpha Naloxol靶点实验

查看更多实验

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6-Alpha Naloxol英文别名

• 6a-Naloxol
• 6-Alpha Naloxol