DDMS

• 常用名: DDMS
• 英文名: DDMS
• CAS号: 206052-03-1
• 分子量: 433.200
• 密度: 1.5±0.1 g/cm3
• 沸点: N/A
• 分子式: C₁₃H₂₃Br₂NO₃S
• 熔点: N/A
• 闪点: N/A

DDMS用途

DDMS (Dibromo-dodecenyl-methylsulfimide) 是一种选择性 20-HETE 生产抑制剂。DDMS 可减弱硝普钠 (SNP) 的血管舒张反应。

DDMS名称

• 中文名: DDMS
• 英文名: 12,12-dibromo-N-methylsulfonyldodec-11-enamide

DDMS生物活性

• 描述: DDMS (Dibromo-dodecenyl-methylsulfimide) 是一种选择性 20-HETE 生产抑制剂。DDMS 可减弱硝普钠 (SNP) 的血管舒张反应。
• 相关类别:
  研究领域 >> 心血管疾病
  信号通路 >> 代谢酶/蛋白酶 >> 细胞色素P450
• 靶点实验:

  20-HETE[1]

• 参考文献:

  [1]. Alonso-Galicia M, et al. Inhibition of 20-HETE production contributes to the vascular responses to nitric oxide. Hypertension. 1997 Jan;29(1 Pt 2):320-5.

DDMS物理化学性质

• 密度: 1.5±0.1 g/cm3
• 分子式: C₁₃H₂₃Br₂NO₃S
• 分子量: 433.200
• 精确质量: 430.976532
• PSA: 71.62000
• LogP: 4.26
• InChIKey: BDCZFOHEQGRTBW-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)NC(=O)CCCCCCCCCC=C(Br)Br
• 折射率: 1.533
• 储存条件: -20°C，密闭，干燥

DDMS靶点实验

查看更多实验

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：A screen for small molecules that modulate mitochondrial supercomplex formation 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1482

实验名称：Inhibitory activity against 20-Hydroxy-5,8,11,14-eicosatetraenoic acid synthase from ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL831871

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

实验名称：Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu... 来源：15621 靶标：G protein-activated inward rectifier potassium channel 2 External Id：VANDERBILT_HTS_GIRK2_MPD

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DDMS英文别名

• 12,12-dibromo-N-(methylsulfonyl)dodec-11-enamide
• 12,12-Dibromo-N-(methylsulfonyl)-11-dodecenamide