硫酸奎宁水合物结构式
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常用名 | 硫酸奎宁水合物 | 英文名 | Quinine hemisulfate hydrate |
|---|---|---|---|---|
| CAS号 | 207671-44-1 | 分子量 | 782.94300 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C20H24N2O2.1/2H2O4S.H2O | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
硫酸奎宁水合物用途Quinine hemisulfate hydrate 是一种从金鸡纳树皮中提取的生物碱,具有抗疟疾的作用。Quinine hemisulfate hydrate 是一种钾离子通道 (potassium channel) 抑制剂,可抑制电压脉冲引起的 MT mSlo3 (KCa5.1) 通道 +100 mV 电流, 其 IC50 值为 169 μM。 |
| 中文名 | 奎宁 半硫酸盐 一水合物 |
|---|---|
| 英文名 | Hydrogen sulfate-(8α,9R)-6'-methoxycinchonan-9-ol hydrate (2:1: 2:2) |
| 中文别名 | 奎宁半硫酸盐一水合物 |
| 英文别名 | 更多 |
| 描述 | Quinine hemisulfate hydrate 是一种从金鸡纳树皮中提取的生物碱,具有抗疟疾的作用。Quinine hemisulfate hydrate 是一种钾离子通道 (potassium channel) 抑制剂,可抑制电压脉冲引起的 MT mSlo3 (KCa5.1) 通道 +100 mV 电流, 其 IC50 值为 169 μM。 |
|---|---|
| 相关类别 | |
| 靶点 |
IC50: Parasite[1], 169 μM (mSlo3)[2] |
| 参考文献 |
| 分子式 | C20H24N2O2.1/2H2O4S.H2O |
|---|---|
| 分子量 | 782.94300 |
| 精确质量 | 782.35600 |
| PSA | 192.62000 |
| LogP | 6.52160 |
| 储存条件 | -20°C，干燥，密封 |
| 符号 |
GHS07 |
|---|---|
| 信号词 | Warning |
| 危害声明 | H315-H319-H335 |
| 警示性声明 | P261-P305 + P351 + P338 |
| 个人防护装备 | dust mask type N95 (US);Eyeshields;Gloves |
| 危害码 (欧洲) | Xi |
| 危险品运输编码 | NONH for all modes of transport |
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Interaction of quinine sulfate with anionic micelles of sodium dodecylsulfate: A time-resolved fluorescence spectroscopy at different pH.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 148 , 49-59, (2015) Photophysical behavior and rotational relaxation dynamics of quinine sulfate (QS) in anionic surfactant, sodium dodecylsulfate (SDS) at different pH have been studied using steady state and time resol... |
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The uptake of trehalose glycolipids by macrophages is independent of Mincle.
ChemBioChem. 16(4) , 683-93, (2015) Trehalose glycolipids play an important role in the pathogenesis of Mycobacterium tuberculosis and are used as adjuvants for vaccines; however, much still remains unanswered about the mechanisms throu... |
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In vivo antimalarial activity and mechanisms of action of 4-nerolidylcatechol derivatives.
Antimicrob. Agents Chemother. 59 , 3271-80, (2015) 4-Nerolidylcatechol (1) is an abundant antiplasmodial metabolite that is isolated from Piper peltatum roots. O-Acylation or O-alkylation of compound 1 provides derivatives exhibiting improved stabilit... |
| Quinine hemisulfate |
| Quinine sulfate |
