盐酸洛非西定

• 常用名: 盐酸洛非西定
• 英文名: Lofexidine hydrochloride
• CAS号: 21498-08-8
• 分子量: 295.593
• 密度: N/A
• 沸点: 421.5ºC at 760 mmHg
• 分子式: C₁₁H₁₃Cl₃N₂O
• 熔点: 230-232ºC
• 闪点: 208.7ºC
• 符号: GHS06
• 信号词: Danger

盐酸洛非西定用途

Lofexidine盐酸盐是一种α2A肾上腺素受体激动剂, 常用于缓解海洛因和其他阿片类戒断的躯体症状。

盐酸洛非西定名称

• 中文名: 盐酸洛非西定
• 英文名: Lofexidine Hydrochloride
• 中文别名: 2-[1-(2,6-二氯苯氧基)乙基]-2-咪唑啉盐酸盐

盐酸洛非西定生物活性

• 描述: Lofexidine盐酸盐是一种α2A肾上腺素受体激动剂, 常用于缓解海洛因和其他阿片类戒断的躯体症状。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体
  研究领域 >> 神经疾病

盐酸洛非西定物理化学性质

• 沸点: 421.5ºC at 760 mmHg
• 熔点: 230-232ºC
• 分子式: C₁₁H₁₃Cl₃N₂O
• 分子量: 295.593
• 闪点: 208.7ºC
• 精确质量: 294.009338
• PSA: 33.62000
• LogP: 3.32880
• InChIKey: DWWHMKBNNNZGHF-UHFFFAOYSA-N
• SMILES: CC(Oc1c(Cl)cccc1Cl)C1=NCCN1.Cl
• 外观性状: 固体
• 蒸汽压: 6.35E-07mmHg at 25°C
• 储存条件: -20°C Freezer

盐酸洛非西定MSDS

盐酸洛非西定MSDS英文版

盐酸洛非西定毒性和生态

盐酸洛非西定安全信息

• 符号: GHS06
• 信号词: Danger
• 危害声明: H301
• 警示性声明: P301 + P310
• 危害码 (欧洲): T
• 风险声明 (欧洲): 25
• 安全声明 (欧洲): 45
• 危险品运输编码: 2811.0
• 危险类别: 6.1
• 海关编码: 2933290090

盐酸洛非西定海关

• 海关编码: 2933290090
• 中文概述: 2933290090. 其他结构含非稠合咪唑环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

盐酸洛非西定靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020);... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4296184

实验名称：Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL4296186

实验名称：Primary cell-based high-throughput screening for identification of compounds that all... 来源：Johns Hopkins Ion Channel Center 靶标：MAS-related GPR member X1 [Homo sapiens] External Id：JHICC_MrgX1_AlloAgonist_Primary

实验名称：Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CA... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL4296185

实验名称：Primary cell-based high-throughput screening for identification of compounds that ant... 来源：Johns Hopkins Ion Channel Center 靶标：MAS-related GPR member X1 [Homo sapiens] External Id：JHICC_MrgX1_Antagonist_Primary

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Identifying Sarm1 Tir Hydrolase inhibitors through NAD-Glo assay 来源：24386 靶标：N/A External Id：Sarm1 Tir NADase inhibitors screen

实验名称：uHTS identification of small molecule inhibitors of tim10-1 yeast via a luminescent a... 来源：Burnham Center for Chemical Genomics 靶标：TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner membrane [Saccharomyces cerevisiae S288c] External Id：SBCCG-A413-tim10-1-Primary-Antagonist-Assay

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盐酸洛非西定英文别名

• 2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole hydrochloride (1:1)
• Lofexidine HCl
• 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole,hydrochloride
• RMI 14042A
• 1H-Imidazole, 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-, hydrochloride (1:1)
• Lofexidine hydrochloride
• UNII:V47G1SDI1B
• MFCD00917022
• 2-(1-(2,6-Dichlorophenoxy)ethyl)-4,5-dihydro-1H-imidazole Monohydrochloride
• (±)-2-(1-(2,6-Dichlorophenoxy)ethyl)-2-imidazoline Hydrochloride