5-Desmethylsinensetin

• 常用名: 5-Desmethylsinensetin
• 英文名: 5-Demethylsinensetin
• CAS号: 21763-80-4
• 分子量: 358.34200
• 密度: 1.309g/cm3
• 沸点: 556.8ºC at 760mmHg
• 分子式: C₁₉H₁₈O₇
• 熔点: N/A
• 闪点: 200.7ºC

5-Desmethylsinensetin用途

5-desmethylsinensetin 可从 Stevia satureiifolia var. satureiifolia 中分离得到,具有抗原生动物的活性。5-desmethylsinensetin 对 T. cruzi epimastigotes 和trypomastigotes 的 IC50 值分别为 0.4 μg/mL 和75.1 μg/mL。

5-Desmethylsinensetin名称

• 中文名: 5-羟基-3',4',6,7-四甲氧基黄酮
• 英文名: 2-(3,4-dimethoxyphenyl)-5-hydroxy-6,7-dimethoxychromen-4-one

5-Desmethylsinensetin生物活性

• 描述: 5-desmethylsinensetin 可从 Stevia satureiifolia var. satureiifolia 中分离得到,具有抗原生动物的活性。5-desmethylsinensetin 对 T. cruzi epimastigotes 和trypomastigotes 的 IC50 值分别为 0.4 μg/mL 和75.1 μg/mL。
• 相关类别:
  研究领域 >> 感染
  研究领域 >> 炎症/免疫
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. María Florencia Beer, et al. Trypanocidal and leishmanicidal activities of flavonoids isolated from Stevia satureiifolia var. satureiifolia. Pharm Biol. 2016 Oct;54(10):2188-95.

5-Desmethylsinensetin物理化学性质

• 密度: 1.309g/cm3
• 沸点: 556.8ºC at 760mmHg
• 分子式: C₁₉H₁₈O₇
• 分子量: 358.34200
• 闪点: 200.7ºC
• 精确质量: 358.10500
• PSA: 87.36000
• LogP: 3.20000
• InChIKey: QEWSAPKRFOFQIU-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2cc(=O)c3c(O)c(OC)c(OC)cc3o2)cc1OC
• 蒸汽压: 5.27E-13mmHg at 25°C
• 折射率: 1.593
• 储存条件: 2-8℃

5-Desmethylsinensetin安全信息

• 海关编码: 2914509090

5-Desmethylsinensetin海关

• 海关编码: 2914509090
• 中文概述: 2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途, 丙酮报明包装
• Summary: HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

5-Desmethylsinensetin靶点实验

查看更多实验

实验名称：Inhibition of recombinant human CYP1B1 expressed in baker's yeast-derived microsomes ... 来源：ChEMBL 靶标：Cytochrome P450 1B1 External Id：CHEMBL4257966

实验名称：Inhibition of recombinant human CYP1A2 expressed in baker's yeast-derived microsomes ... 来源：ChEMBL 靶标：Cytochrome P450 1A2 External Id：CHEMBL4257965

实验名称：Inhibition of recombinant human CYP3A4 expressed in baker's yeast-derived microsomes ... 来源：ChEMBL 靶标：Cytochrome P450 3A4 External Id：CHEMBL4257968

实验名称：Inhibition of recombinant human CYP2D6 expressed in baker's yeast-derived microsomes ... 来源：ChEMBL 靶标：Cytochrome P450 2D6 External Id：CHEMBL4257967

实验名称：Inhibition of recombinant human CYP1A1 expressed in baker's yeast-derived microsomes ... 来源：ChEMBL 靶标：Cytochrome P450 1A1 External Id：CHEMBL4257963

实验名称：Inhibition of human recombinant CYP1B1 expressed in HEK293 cells using 7-ethoxyresoru... 来源：ChEMBL 靶标：Cytochrome P450 1B1 External Id：CHEMBL4257974

实验名称：Cytotoxicity against human KB cells 来源：ChEMBL 靶标：KB External Id：CHEMBL966634

实验名称：Inhibition of human recombinant CYP1A2 expressed in HEK293 cells using 3-cyano-7-etho... 来源：ChEMBL 靶标：Cytochrome P450 1A2 External Id：CHEMBL4257973

实验名称：Inhibition of human recombinant CYP2C9 expressed in HEK293 cells using 3-cyano-7-etho... 来源：ChEMBL 靶标：Cytochrome P450 2C9 External Id：CHEMBL4257976

实验名称：Inhibition of human recombinant CYP2D6 expressed in HEK293 cells using 7-ethoxy-methy... 来源：ChEMBL 靶标：Cytochrome P450 2D6 External Id：CHEMBL4257975

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5-Desmethylsinensetin英文别名

• 5-demethylsinensetin
• 5-Hydroxy-3',4',6,7-tetramethoxyflavone
• HTMF
• 3'-O-methyleupatorin
• 6,7,4',5'-tetramethoxy-5-monohydroxyflavone
• 5-desmethylsinensetin