盐酸奥兰西丁半水合物

更新时间：2025-08-25 11:14:56

盐酸奥兰西丁半水合物结构式	常用名	盐酸奥兰西丁半水合物	英文名	Olanexidine Hydrochloride semihydrate
	CAS号	218282-71-4	分子量	835.60900
	密度	N/A	沸点	503.3ºC at 760 mmHg
	分子式	C₃₄H₅₈Cl₆N₁₀O	熔点	N/A
	MSDS	N/A	闪点	258.2ºC

盐酸奥兰西丁半水合物用途

Olanexidine hydrochloride semihydrate 是一种抗菌剂。Olanexidine hydrochloride semihydrate 对多种细菌都有抗菌活性,包括革兰氏阳性和革兰氏阴性细菌。Olanexidine hydrochloride semihydrate 也是一种防腐剂。Olanexidine hydrochloride semihydrate 可用于感染和炎症的研究。

中文名	盐酸奥兰西丁半水合物
英文名	1-[N'-[(3,4-dichlorophenyl)methyl]carbamimidoyl]-2-octylguanidine,hydrate,dihydrochloride
英文别名	更多

描述	Olanexidine hydrochloride semihydrate 是一种抗菌剂。Olanexidine hydrochloride semihydrate 对多种细菌都有抗菌活性,包括革兰氏阳性和革兰氏阴性细菌。Olanexidine hydrochloride semihydrate 也是一种防腐剂。Olanexidine hydrochloride semihydrate 可用于感染和炎症的研究。
相关类别	研究领域 >> 感染研究领域 >> 炎症/免疫信号通路 >> 抗感染 >> 细菌
参考文献	[1]. Hagi A, et al. Bactericidal Effects and Mechanism of Action of Olanexidine Gluconate, a New Antiseptic. Antimicrob Agents Chemother. 2015 Aug;59(8):4551-9. [2]. Nii T, Yumoto H, Hirota K, Miyake Y. Anti-inflammatory effects of olanexidine gluconate on oral epithelial cells. BMC Oral Health. 2019 Nov 8;19(1):239. [3]. Imai K, et al. Disinfection efficacy and mechanism of olanexidine gluconate against norovirus. Am J Infect Control. 2022 Jul;50(7):764-771. [4]. Nakata H, et al. Effects of olanexidine gluconate on preoperative skin preparation: an experimental study in cynomolgus monkeys. J Med Microbiol. 2017 May;66(5):678-685.

描述

相关类别

研究领域 >> 感染

研究领域 >> 炎症/免疫

信号通路 >> 抗感染 >> 细菌

参考文献

[1]. Hagi A, et al. Bactericidal Effects and Mechanism of Action of Olanexidine Gluconate, a New Antiseptic. Antimicrob Agents Chemother. 2015 Aug;59(8):4551-9.

[2]. Nii T, Yumoto H, Hirota K, Miyake Y. Anti-inflammatory effects of olanexidine gluconate on oral epithelial cells. BMC Oral Health. 2019 Nov 8;19(1):239.

[3]. Imai K, et al. Disinfection efficacy and mechanism of olanexidine gluconate against norovirus. Am J Infect Control. 2022 Jul;50(7):764-771.

[4]. Nakata H, et al. Effects of olanexidine gluconate on preoperative skin preparation: an experimental study in cynomolgus monkeys. J Med Microbiol. 2017 May;66(5):678-685.

沸点	503.3ºC at 760 mmHg
分子式	C₃₄H₅₈Cl₆N₁₀O
分子量	835.60900
闪点	258.2ºC
精确质量	832.29300
PSA	176.81000
LogP	13.26850
InChIKey	MVYKMBTTXLGRAY-UHFFFAOYSA-N
SMILES	CCCCCCCCN=C(N)NC(N)=NCc1ccc(Cl)c(Cl)c1.Cl.Cl.O
蒸汽压	2.96E-10mmHg at 25°C

实验名称：Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 after 3 mins.
来源：ChEMBL
靶标：Pseudomonas aeruginosa
External Id：CHEMBL764782

实验名称：Antibacterial activity against Escherichia coli after 3 mins.
来源：ChEMBL
靶标：Escherichia coli
External Id：CHEMBL681203

实验名称：Antibacterial activity against Burkholderia cepacia 10 after 3 mins.
来源：ChEMBL
靶标：Burkholderia cepacia
External Id：CHEMBL648222

实验名称：Antibacterial activity against Enterococcus faecalis IFO 12580 after 30 seconds
来源：ChEMBL
靶标：Enterococcus faecalis
External Id：CHEMBL679063

实验名称：Antibacterial activity against Staphylococcus aureus after 3 mins.
来源：ChEMBL
靶标：Staphylococcus aureus
External Id：CHEMBL809599

实验名称：Antibacterial activity against Staphylococcus aureus FDA 209P after 30 seconds
来源：ChEMBL
靶标：Staphylococcus aureus
External Id：CHEMBL809424

实验名称：Antibacterial activity against Serratia marcescens IFO 12648 after 30 seconds
来源：ChEMBL
靶标：Serratia marcescens
External Id：CHEMBL805911

实验名称：Antibacterial activity against Staphylococcus epidermidis ATCC 12228 after 30 seconds
来源：ChEMBL
靶标：Staphylococcus epidermidis
External Id：CHEMBL813755

实验名称：Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 after 30 seconds
来源：ChEMBL
靶标：Pseudomonas aeruginosa
External Id：CHEMBL768916

实验名称：Antibacterial activity against methicillin-resistant Staphylococcus aureus 57 after 3...
来源：ChEMBL
靶标：Staphylococcus aureus
External Id：CHEMBL809602

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