蒺藜皂苷

• 常用名: 蒺藜皂苷
• 英文名: Tribuloside
• CAS号: 22153-44-2
• 分子量: 594.52000
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₀H₂₆O₁₃
• 熔点: N/A
• 闪点: N/A

蒺藜皂苷用途

Tribuloside,蒺藜皂苷从 Potentilla multifid 中分离出来。Tribuloside 对非致病性分枝杆菌属具有抗分枝杆菌活性,最低抑菌浓度 (MIC) 为 5.0 mg/mL。Tribuloside 具有 1,1-二苯基-2-苦基肼基清除活性。Tribuloside 具有抗抑郁作用,改善抑郁模型大鼠的行为。

蒺藜皂苷名称

• 中文名: 刺蒺藜皂甙
• 英文名: [(2R,3S,4S,5R,6S)-6-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl (Z)-3-(4-hydroxyphenyl)prop-2-enoate
• 中文别名: 蒺藜皂苷 | 蒺藜甙 A

蒺藜皂苷生物活性

• 描述: Tribuloside,蒺藜皂苷从 Potentilla multifid 中分离出来。Tribuloside 对非致病性分枝杆菌属具有抗分枝杆菌活性,最低抑菌浓度 (MIC) 为 5.0 mg/mL。Tribuloside 具有 1,1-二苯基-2-苦基肼基清除活性。Tribuloside 具有抗抑郁作用,改善抑郁模型大鼠的行为。
• 相关类别:
  研究领域 >> 感染
  研究领域 >> 神经疾病
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Christopher R, et al. A new cinnamoylglycoflavonoid, antimycobacterial and antioxidant constituents from Heritiera littoralis leaf extracts. Nat Prod Res. 2014;28(6):351-8.

  [2]. SHEN Shuang-hong, et al. Effect of tribuloside on geurogenesis in dentate gyrus of chronic stress depression rats. Acta Chinese Medicine & Pharmacology,2008,36(3) :13-16.

蒺藜皂苷物理化学性质

• 分子式: C₃₀H₂₆O₁₃
• 分子量: 594.52000
• 精确质量: 594.13700
• PSA: 216.58000
• LogP: 1.72540
• InChIKey: DVGGLGXQSFURLP-PYFXTMFGSA-N
• SMILES: O=C(C=Cc1ccc(O)cc1)OCC1OC(Oc2c(-c3ccc(O)cc3)oc3cc(O)cc(O)c3c2=O)C(O)C(O)C1O
• 蒸汽压: 0mmHg at 25°C
• 储存条件: 2-8℃，避光，密封

蒺藜皂苷靶点实验

查看更多实验

实验名称：Inhibition of JNK phosphorylation in DNP-BSA-stimulated rat RBL2H3 cells by Western b... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1053246

实验名称：Inhibition of Syk phosphorylation in DNP-BSA-stimulated rat RBL2H3 cells by Western b... 来源：ChEMBL 靶标：Tyrosine-protein kinase SYK External Id：CHEMBL1053244

实验名称：Inhibition of ERK phosphorylation in DNP-BSA-stimulated rat RBL2H3 cells by Western b... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1053245

实验名称：Inhibition of recombinant human IDH1 R132H mutant extracted from Escherichia coli BL2... 来源：ChEMBL 靶标：Isocitrate dehydrogenase [NADP] cytoplasmic External Id：CHEMBL5608699

实验名称：Inhibition of recombinant human wildtype IDH1 extracted from Escherichia coli BL21 (D... 来源：ChEMBL 靶标：Isocitrate dehydrogenase [NADP] cytoplasmic External Id：CHEMBL5608700

实验名称：Inhibition of IDH1 R132H mutant in human U-87 MG cells assessed as reduction in 2-HG ... 来源：ChEMBL 靶标：Isocitrate dehydrogenase [NADP] cytoplasmic External Id：CHEMBL5608708

实验名称：Antimicrobial activity against Cryptococcus neoformans ATCC 208821 at 32 ug/ml after ... 来源：ChEMBL 靶标：Cryptococcus neoformans External Id：CHEMBL4192096

实验名称：Inhibition of diphenolase activity of mushroom tyrosinase at 0.056 mM 来源：ChEMBL 靶标：Polyphenol oxidase 2 External Id：CHEMBL892352

实验名称：Inhibition of diphenolase activity of mushroom tyrosinase at 0.011 mM 来源：ChEMBL 靶标：Polyphenol oxidase 2 External Id：CHEMBL892353

实验名称：Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins at room... 来源：ChEMBL 靶标：Carbonic anhydrase 1 External Id：CHEMBL3631188

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蒺藜皂苷英文别名

• Tribuloside
• Tribuloside A