MtTMPK-IN-4

• 常用名: MtTMPK-IN-4
• 英文名: MtTMPK-IN-4
• CAS号: 2225889-49-4
• 分子量: 391.46
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₅N₃O₃
• 熔点: N/A
• 闪点: N/A

MtTMPK-IN-4用途

MtTMPK-IN-4(化合物2)是一种对哌啶,是一种有效的结核分枝杆菌胸苷酸激酶(MtTMPK)抑制剂,IC50为6.1μM。MtTMPK-IN-4是一种有效的酪氨酸酶抑制剂。MtTMPK-IN-4是一种强效抗菌剂[1][2]。

MtTMPK-IN-4名称

• 英文名: MtTMPK-IN-4

MtTMPK-IN-4生物活性

• 描述: MtTMPK-IN-4(化合物2)是一种对哌啶,是一种有效的结核分枝杆菌胸苷酸激酶(MtTMPK)抑制剂,IC50为6.1μM。MtTMPK-IN-4是一种有效的酪氨酸酶抑制剂。MtTMPK-IN-4是一种强效抗菌剂[1][2]。
• 相关类别:
  研究领域 >> 炎症/免疫
  信号通路 >> 代谢酶/蛋白酶 >> 酪氨酸酶
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Lijun Song, et al. Structure Guided Lead Generation toward Nonchiral M. tuberculosis Thymidylate Kinase Inhibitors. J Med Chem. 2018 Apr 12;61(7):2753-2775.

  [2]. Jin Li, et al. Recent advances in the design and discovery of synthetic tyrosinase inhibitors. Eur J Med Chem. 2021 Nov 15;224:113744.

MtTMPK-IN-4物理化学性质

• 分子式: C₂₃H₂₅N₃O₃
• 分子量: 391.46

MtTMPK-IN-4靶点实验

查看更多实验

实验名称：Antimicrobial activity against Mycobacterium tuberculosis H37Ra ATCC 25177 harboring ... 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL4024195

实验名称：Inhibition of Mycobacterium tuberculosis TMPK expressed in Escherichia coli BLi5 usin... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4024193

实验名称：Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by ... 来源：ChEMBL 靶标：Thymidylate kinase External Id：CHEMBL4832952

实验名称：Cytotoxicity against human MRC-5 cells assessed as reduction in cell growth measured ... 来源：ChEMBL 靶标：MRC5 External Id：CHEMBL4832954

实验名称：Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assess... 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL4832953

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