Tubulin polymerization-IN-10

• 常用名: Tubulin polymerization-IN-10
• 英文名: Tubulin polymerization-IN-10
• CAS号: 2238784-19-3
• 分子量: 379.43
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₂₁NO₆S
• 熔点: N/A
• 闪点: N/A

Tubulin polymerization-IN-10用途

微管蛋白聚合-IN-10是一种有效的微管蛋白聚合抑制剂,IC50为4.25±0.75μM。微管蛋白聚合-IN-10具有抗肿瘤作用[1]。

Tubulin polymerization-IN-10名称

• 英文名: Tubulin polymerization-IN-10

Tubulin polymerization-IN-10生物活性

• 描述: 微管蛋白聚合-IN-10是一种有效的微管蛋白聚合抑制剂,IC50为4.25±0.75μM。微管蛋白聚合-IN-10具有抗肿瘤作用[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 细胞周期/DNA损伤 >> 微管/微管蛋白
  信号通路 >> 细胞骨架 >> 微管/微管蛋白
• 参考文献:

  [1]. Huajian Zhu, et al. Design, synthesis and biological evaluation of vinyl selenone derivatives as novel microtubule polymerization inhibitors. Eur J Med Chem . 2020 Dec 1;207:112716.

Tubulin polymerization-IN-10物理化学性质

• 分子式: C₁₈H₂₁NO₆S
• 分子量: 379.43
• InChIKey: ZNQCSGBWWWHXOY-BQYQJAHWSA-N
• SMILES: COc1ccc(C=CS(=O)(=O)c2cc(OC)c(OC)c(OC)c2)cc1N

Tubulin polymerization-IN-10靶点实验

查看更多实验

实验名称：Antitumor activity against mouse H22 cells implanted in ICR mouse assessed as tumor g... 来源：ChEMBL 靶标：H22 External Id：CHEMBL4275506

实验名称：Toxicity in ICR mouse implanted with mouse H22 cells assessed as decrease in body wei... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4275505

实验名称：Antitumor activity against mouse H22 cells implanted in ICR mouse assessed as tumor g... 来源：ChEMBL 靶标：H22 External Id：CHEMBL4275502

实验名称：Antitumor activity against mouse H22 cells implanted in ICR mouse assessed as tumor g... 来源：ChEMBL 靶标：H22 External Id：CHEMBL4275503

实验名称：Antiproliferative activity against human HCT8 cells assessed as inhibition of cell gr... 来源：ChEMBL 靶标：HCT-8 External Id：CHEMBL4774334

实验名称：Inhibition of pig brain tubulin polymerization preincubated with compound followed by... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4774335

实验名称：Antiproliferative activity against human K562 cells assessed as inhibition of cell gr... 来源：ChEMBL 靶标：K562 External Id：CHEMBL4774332

实验名称：Antiproliferative activity against human HepG2 cells assessed as inhibition of cell g... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL4774333

实验名称：Induction of apoptosis in human K562 cells at 0.05 uM after 48 hrs by Annexin V-FITC/... 来源：ChEMBL 靶标：K562 External Id：CHEMBL4275492

实验名称：Cell cycle arrest in human K562 cells assessed as accumulation at G2/M phase after 48... 来源：ChEMBL 靶标：K562 External Id：CHEMBL4275491

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