8,9-环氧-9,10-二异丁酰百里草酚

• 常用名: 8,9-环氧-9,10-二异丁酰百里草酚
• 英文名: 8,9-epoxy-3,10-diisobutyryloxythymol
• CAS号: 22518-06-5
• 分子量: 320.38000
• 密度: 1.123±0.06 g/cm3
• 沸点: N/A
• 分子式: C₁₈H₂₄O₅
• 熔点: N/A
• 闪点: N/A

8,9-环氧-9,10-二异丁酰百里草酚用途

10-Isobutyryloxy-8,9-epoxythymol isobutyrate 是 Inula helenium 和 Inula royleana 根培养物的主要成分。10-Isobutyryloxy-8,9-epoxythymol isobutyrate 具有适度的抗菌活性,抑制 Staphylococcus aureus FDA 209 P, Staphylococcus aureus,Enterococcus faecalis,Candida albicans 和 Pseudomonas aeruginosa 的 MIC 分别为50,250,250,250 和 1000 μg/mL。

8,9-环氧-9,10-二异丁酰百里草酚名称

• 中文名: 10-异丁酰氧基-8,9-环氧麝香草酚异丁酸酯
• 英文名: 10-isobutyryloxy-8,9-epoxythymyl isobutyrate
• 中文别名: 8,9-环氧-9,10-二异丁酰百里草酚

8,9-环氧-9,10-二异丁酰百里草酚生物活性

• 描述: 10-Isobutyryloxy-8,9-epoxythymol isobutyrate 是 Inula helenium 和 Inula royleana 根培养物的主要成分。10-Isobutyryloxy-8,9-epoxythymol isobutyrate 具有适度的抗菌活性,抑制 Staphylococcus aureus FDA 209 P, Staphylococcus aureus,Enterococcus faecalis,Candida albicans 和 Pseudomonas aeruginosa 的 MIC 分别为50,250,250,250 和 1000 μg/mL。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Stojakowska A, et al. Antimicrobial activity of 10-isobutyryloxy-8,9-epoxythymol isobutyrate. Fitoterapia. 2005 Dec;76(7-8):687-90.

8,9-环氧-9,10-二异丁酰百里草酚物理化学性质

• 密度: 1.123±0.06 g/cm3
• 分子式: C₁₈H₂₄O₅
• 分子量: 320.38000
• 精确质量: 320.16200
• PSA: 65.13000
• LogP: 2.98110
• InChIKey: OLARKEMZPWGFJU-UHFFFAOYSA-N
• SMILES: Cc1ccc(C2(COC(=O)C(C)C)CO2)c(OC(=O)C(C)C)c1
• 水溶解性: Practically insoluble (0.054 g/L) (25 ºC)

8,9-环氧-9,10-二异丁酰百里草酚安全信息

• 危害码 (欧洲): Xn
• 风险声明 (欧洲): 22-36
• 安全声明 (欧洲): 26
• WGK德国: 3

8,9-环氧-9,10-二异丁酰百里草酚靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Primary qHTS for Identification of Calcium Integrin Binding Protein 1 (CIB1) Competit... 来源：NCGC External Id：CIB1-p1-p2

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8,9-环氧-9,10-二异丁酰百里草酚英文别名

• isobutyrate 10-isobutyryloxy-8,9-epoxythymyle
• 8,9-epoxy-10-isobutyryloxythymyl isobutyrate
• Isobutyric acid 2-(2-isobutyryloxy-4-methyl-phenyl)-oxiranylmethyl ester
• 8,9-epoxy-3,10-diisobutanoyloxy-p-cymene
• 2-isobutyryloxymethyl-2-(2-isobutyryloxy-4-methyl-phenyl)-oxirane
• 8,9-epoxy-3,10-diisobutyryloxythymol