酒石酸艾芬地尔

更新时间：2025-08-25 12:39:21

酒石酸艾芬地尔结构式	常用名	酒石酸艾芬地尔	英文名	ifenprodil tartrate
	CAS号	23210-58-4	分子量	400.49
	密度	N/A	沸点	493.5ºC at 760mmHg
	分子式	C₂₁H₂₇NO_2.1/₂C₄H₆O₆	熔点	178-180ºC
	MSDS	中文版美版	闪点	248.7ºC
	符号	GHS07	信号词	Warning

酒石酸艾芬地尔用途

Ifenprodil tartrate 是 NMDA受体拮抗剂，选择性抑制含NR2B亚基受体。

中文名	酒石酸艾芬地尔
英文名	ifenprodil hemitartrate
中文别名	抗坏血酸钠.维丙钠
英文别名	更多

描述	Ifenprodil tartrate 是 NMDA受体拮抗剂,选择性抑制含NR2B亚基受体。
相关类别	信号通路 >> 跨膜转运 >> iGluR 信号通路 >> 神经信号通路 >> iGluR 研究领域 >> 神经疾病
参考文献	[1]. Gotti B, et al. Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. I. Evidence for efficacy in models of focal cerebral ischemia. J Pharmacol Exp Ther. 1988 Dec;247(3):1211-21. [2]. Reynolds IJ, et al. Ifenprodil is a novel type of N-methyl-D-aspartate receptor antagonist: interaction with polyamines. Mol Pharmacol. 1989 Nov;36(5):758-65. [3]. Schoemaker H, et al. Binding of [3H]ifenprodil, a novel NMDA antagonist, to a polyamine-sensitive site in the rat cerebral cortex. Eur J Pharmacol. 1990 Feb 6;176(2):249-50. [4]. Shalaby IA, et al. Neuroprotective effects of the N-methyl-D-aspartate receptor antagonists ifenprodil and SL-82,0715 on hippocampal cells in culture. J Pharmacol Exp Ther. 1992 Feb;260(2):925-32.

描述

Ifenprodil tartrate 是 NMDA受体拮抗剂,选择性抑制含NR2B亚基受体。

相关类别

信号通路 >> 跨膜转运 >> iGluR

信号通路 >> 神经信号通路 >> iGluR

研究领域 >> 神经疾病

参考文献

[1]. Gotti B, et al. Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. I. Evidence for efficacy in models of focal cerebral ischemia. J Pharmacol Exp Ther. 1988 Dec;247(3):1211-21.

[2]. Reynolds IJ, et al. Ifenprodil is a novel type of N-methyl-D-aspartate receptor antagonist: interaction with polyamines. Mol Pharmacol. 1989 Nov;36(5):758-65.

[3]. Schoemaker H, et al. Binding of [3H]ifenprodil, a novel NMDA antagonist, to a polyamine-sensitive site in the rat cerebral cortex. Eur J Pharmacol. 1990 Feb 6;176(2):249-50.

[4]. Shalaby IA, et al. Neuroprotective effects of the N-methyl-D-aspartate receptor antagonists ifenprodil and SL-82,0715 on hippocampal cells in culture. J Pharmacol Exp Ther. 1992 Feb;260(2):925-32.

沸点	493.5ºC at 760mmHg
熔点	178-180ºC
分子式	C₂₁H₂₇NO_2.1/₂C₄H₆O₆
分子量	400.49
闪点	248.7ºC
PSA	158.76000
LogP	1.58410
InChIKey	DMPRDSPPYMZQBT-CEAXSRTFSA-N
SMILES	CC(C(O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1.CC(C(O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1.O=C(O)C(O)C(O)C(=O)O
蒸汽压	0mmHg at 25°C
储存条件	Refrigerator

符号	GHS07
信号词	Warning
危害声明	H302-H312-H315-H319-H332-H335
警示性声明	P261-P280-P305 + P351 + P338
个人防护装备	dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲)	Xn: Harmful;
风险声明 (欧洲)	R20/21/22;R36/37/38
安全声明 (欧洲)	22-26-36-36/37
危险品运输编码	NONH for all modes of transport
WGK德国	3

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实验名称：LOPAC HTS for Inhibitors of Aerobactin Synthetase IucA
来源：23265
靶标：IucA from hypervirulent Klebsiella pneumoniae
External Id：IucA Pilot Assay LOPAC Library

实验名称：HTS to identify compounds that affect the blood-brain barrier permeability in vitro
来源：26908
靶标：N/A
External Id：HTS97080

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Ifenprodil Tartrate

Ifenprodil (+)-tartrate salt

Ifenprodil (tartrate)