1,4-Naphthalenedione,2-phenyl

• 常用名: 1,4-Naphthalenedione,2-phenyl
• 英文名: 1,4-Naphthalenedione,2-phenyl
• CAS号: 2348-77-8
• 分子量: 234.25
• 密度: 1.268g/cm3
• 沸点: 414.3ºC at 760mmHg
• 分子式: C₁₆H₁₀O₂
• 熔点: N/A
• 闪点: 155ºC

1,4-Naphthalenedione,2-phenyl用途

抗感染剂1(化合物3a)是一种有效和选择性的抗原虫和抗细菌剂。抗感染剂1对恶性疟原虫和罗得西亚布氏疟原虫具有抗寄生虫活性,IC50值分别为10.95和0.06μM。抗感染剂1对耻垢分枝杆菌具有抗分枝杆菌活性,MIC为8μg/mL【1】。

1,4-Naphthalenedione,2-phenyl名称

• 英文名: 2-phenylnaphthalene-1,4-dione

1,4-Naphthalenedione,2-phenyl生物活性

• 描述: 抗感染剂1(化合物3a)是一种有效和选择性的抗原虫和抗细菌剂。抗感染剂1对恶性疟原虫和罗得西亚布氏疟原虫具有抗寄生虫活性,IC50值分别为10.95和0.06μM。抗感染剂1对耻垢分枝杆菌具有抗分枝杆菌活性,MIC为8μg/mL【1】。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Kalt MM, et al. Palladium-catalysed synthesis of arylnaphthoquinones as antiprotozoal and antimycobacterial agents. Eur J Med Chem. 2020 Dec 1;207:112837.

1,4-Naphthalenedione,2-phenyl物理化学性质

• 密度: 1.268g/cm3
• 沸点: 414.3ºC at 760mmHg
• 分子式: C₁₆H₁₀O₂
• 分子量: 234.25
• 闪点: 155ºC
• 精确质量: 234.06800
• PSA: 34.14000
• LogP: 3.14920
• InChIKey: CIDYIYSNDAJNGX-UHFFFAOYSA-N
• SMILES: O=C1C=C(c2ccccc2)C(=O)c2ccccc21
• 蒸汽压: 4.51E-07mmHg at 25°C
• 折射率: 1.649

1,4-Naphthalenedione,2-phenyl安全信息

• 海关编码: 2914690090

1,4-Naphthalenedione,2-phenyl海关

• 海关编码: 2914690090
• 中文概述: 2914690090 其他醌. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
• Summary: 2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

1,4-Naphthalenedione,2-phenyl靶点实验

查看更多实验

实验名称：Antibacterial activity against Enterobacter cloacae PCM 2569 after 20 hrs by microbro... 来源：ChEMBL 靶标：Enterobacter cloacae External Id：CHEMBL3878465

实验名称：Antibacterial activity against Proteus vulgaris PCM 2668 after 20 hrs by microbroth d... 来源：ChEMBL 靶标：Proteus vulgaris External Id：CHEMBL3878466

实验名称：Antibacterial activity against Salmonella bongori PCM 2552 after 20 hrs by microbroth... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3878467

实验名称：Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：ORF 73 [Human herpesvirus 8 type M] External Id：HMS791

实验名称：Trypanocidal activity against Trypanosoma cruzi Y strain bloodstream trypomastigotes ... 来源：ChEMBL 靶标：Trypanosoma cruzi External Id：CHEMBL4822985

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：Antibacterial activity against Enterococcus faecalis PCM 2673 after 20 hrs by microbr... 来源：ChEMBL 靶标：Enterococcus faecalis External Id：CHEMBL3878461

实验名称：Antibacterial activity against Pseudomonas aeruginosa PCM 2562 after 20 hrs by microb... 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL3878462

实验名称：Antibacterial activity against Klebsiella pneumoniae PCM1 after 20 hrs by microbroth ... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL3878463

实验名称：Antibacterial activity against Escherichia coli ATCC 8739 after 20 hrs by microbroth ... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL3878464

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1,4-Naphthalenedione,2-phenyl英文别名

• 1.4-Dioxo-2-phenyl-naphthalin-dihydrid-(1.4)
• 1,4-Naphthalenedione,2-phenyl
• 2-phenyl-1,4-naphthalenedione
• 2-phenyl-[1,4]naphthoquinone
• 2-Phenyl-[1,4]naphthochinon
• 1,4-Naphthoquinone,2-phenyl