Cbl-b-IN-1

• 常用名: Cbl-b-IN-1
• 英文名: Cbl-b-IN-1
• CAS号: 2368841-84-1
• 分子量: 498.62
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₉H₃₄N₆O₂
• 熔点: N/A
• 闪点: N/A

Cbl-b-IN-1用途

Cbl-b-IN-1 (example 519) 是 Cbl-b 的抑制剂,信息来自专利 WO2019148005A1,其 IC50 值 <100 nM。

Cbl-b-IN-1名称

• 英文名: Cbl-b-IN-1

Cbl-b-IN-1生物活性

• 描述: Cbl-b-IN-1 (example 519) 是 Cbl-b 的抑制剂,信息来自专利 WO2019148005A1,其 IC50 值 <100 nM。
• 相关类别:
  信号通路 >> 代谢酶/蛋白酶 >> E1/E2/E3酶
  研究领域 >> 炎症/免疫
• 靶点实验:

  IC50: <100 nM (Cbl-b)[1].

• 参考文献:

  [1]. BARSANTI PAUL A (US), et al. INHIBITORS OF CBL-B AND METHODS OF USE THEREOF. WO/2019/148005A1.

Cbl-b-IN-1物理化学性质

• 分子式: C₂₉H₃₄N₆O₂
• 分子量: 498.62
• InChIKey: VXMQSDNIOKDJHW-UHFFFAOYSA-N
• SMILES: Cn1cnnc1CC1(c2cccc(NC(=O)c3cc(CN4CCC5(CC5)C4)cc(C4CC4)n3)c2)COC1

Cbl-b-IN-1靶点实验

查看更多实验

实验名称：Induction of anti-IgM-stimulated human CD20+ B cell activation at 10 to 1000 uM asses... 来源：ChEMBL 靶标：B cell External Id：CHEMBL5051229

实验名称：Induction of anti-CD3/CD28 antibodies-stimulated human T cell activation at 0.3 uM as... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5051165

实验名称：Induction of anti-CD3/CD28 antibodies-stimulated human T cell activation at 1 uM asse... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5051164

实验名称：Induction of anti-CD3/CD28 antibodies-stimulated human T cell activation at 0.3 uM as... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5051170

实验名称：Induction of anti-CD3/CD28 antibodies-stimulated human T cell activation at 1 uM asse... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5051169

实验名称：Induction of activation of human CD56+ CD3- NK cells co-cultured with human K562 cell... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5051232

实验名称：Induction of anti-CD3 antibodies-stimulated human T cell activation at 1 uM assessed ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5051167

实验名称：Induction of anti-CD3 antibodies-stimulated human CD8+ T cell activation in immunocom... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5051222

实验名称：Induction of anti-CD3 antibodies-stimulated human CD8+ T cell activation in immunocom... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5051221

实验名称：Induction of anti-CD3 antibodies-stimulated human CD8+ T cell activation in immunocom... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5051219

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