Microtubule inhibitor 7

• 常用名: Microtubule inhibitor 7
• 英文名: Microtubule inhibitor 7
• CAS号: 2416338-65-1
• 分子量: 446.43
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₁₉FN₂O₅
• 熔点: N/A
• 闪点: N/A

Microtubule inhibitor 7用途

化合物17O(ic50=14.0 nm,NCI-H460)和17p(ic50=2.9 nm,NCI-H460)和呋喃基团在纳摩尔水平上对多种人类癌细胞系显示出有效的细胞毒活性。

Microtubule inhibitor 7名称

• 英文名: Microtubule inhibitor 7

Microtubule inhibitor 7生物活性

• 描述: 化合物17O(ic50=14.0 nm,NCI-H460)和17p(ic50=2.9 nm,NCI-H460)和呋喃基团在纳摩尔水平上对多种人类癌细胞系显示出有效的细胞毒活性。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 细胞周期/DNA损伤 >> 微管/微管蛋白
  信号通路 >> 细胞骨架 >> 微管/微管蛋白
• 参考文献:

  [1]. Ding Z,et al. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer. Bioorg Med Chem. 2020 May 15;28(10):115435.

Microtubule inhibitor 7物理化学性质

• 分子式: C₂₅H₁₉FN₂O₅
• 分子量: 446.43

Microtubule inhibitor 7靶点实验

查看更多实验

实验名称：Inhibition of tubulin in human NCI-H460 cells assessed as inhibition of microtubule p... 来源：ChEMBL 靶标：Tubulin alpha-3C chain External Id：CHEMBL4629254

实验名称：Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability aft... 来源：ChEMBL 靶标：NCI-H460 External Id：CHEMBL4629251

实验名称：Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after ... 来源：ChEMBL 靶标：HT-29 External Id：CHEMBL4629253

实验名称：Cytotoxicity against human BxPC3 cells assessed as reduction in cell viability incuba... 来源：ChEMBL 靶标：BXPC-3 External Id：CHEMBL4629252

共4条，当前第1页，共1页

1