EP-0035985

• 常用名: EP-0035985
• 英文名: EP-0035985
• CAS号: 2499962-44-4
• 分子量: 332.32
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₅F₃N₄
• 熔点: N/A
• 闪点: N/A

EP-0035985用途

EP-0035985(化合物16)是线粒体自噬的激活剂。EP-0035985是EP-0035985[1]的异构体。

EP-0035985名称

• 英文名: EP-0035985

EP-0035985生物活性

• 描述: EP-0035985(化合物16)是线粒体自噬的激活剂。EP-0035985是EP-0035985[1]的异构体。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 自噬 >> 自噬
• 参考文献:

  [1]. De Roulet D, et al. Preparation of purinamines and pyrrolopyrimidinamines, compositions and methods of using the same for treatment of neurodegenerative and mitochondrial disease. World Intellectual Property Organization, WO2020206363 A1 2020-10-08.

EP-0035985物理化学性质

• 分子式: C₁₇H₁₅F₃N₄
• 分子量: 332.32

EP-0035985靶点实验

查看更多实验

实验名称：AUClast in C57BL/6 mouse at 50 mg/kg, po administered as single dose by mass spectrom... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5393610

实验名称：Half-life in mouse at 1 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL5051614

实验名称：AUClast in C57BL/6 mouse at 10 mg/kg, po administered as single dose by mass spectrom... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5393608

实验名称：Activation of PINK1 in human HeLa MKYP PINK1-knock out cells at 3.125 to 6.25 uM asse... 来源：ChEMBL 靶标：Serine/threonine-protein kinase PINK1, mitochondrial External Id：CHEMBL5051612

实验名称：Activation of PINK1 in human iPSC derived neurons at 3.1 to 6.2 uM assessed as reduct... 来源：ChEMBL 靶标：Serine/threonine-protein kinase PINK1, mitochondrial External Id：CHEMBL5051611

实验名称：Half-life in mouse at 10 mg/kg, po 来源：ChEMBL 靶标：N/A External Id：CHEMBL5051618

实验名称：AUC in mouse at 1 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL5051616

实验名称：Observed AUC in mouse at 1 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL5051615

实验名称：Activation of PINK1 in human HeLa MKYP PINK1-knock out cells treated with FCCP/oilgom... 来源：ChEMBL 靶标：Serine/threonine-protein kinase PINK1, mitochondrial External Id：CHEMBL5051606

实验名称：Activation of PINK1 in human HeLa MKYP cells expressing PINK1 treated with FCCP/oilgo... 来源：ChEMBL 靶标：Serine/threonine-protein kinase PINK1, mitochondrial External Id：CHEMBL5051605

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