克林霉素棕榈酸酯盐酸盐

• 常用名: 克林霉素棕榈酸酯盐酸盐
• 英文名: Clindamycin palmitate HCl
• CAS号: 25507-04-4
• 分子量: 699.853
• 密度: N/A
• 沸点: 767.4ºC at 760 mmHg
• 分子式: C₃₄H₆₄Cl₂N₂O₆S
• 熔点: 141-143ºC
• 闪点: 417.9ºC

克林霉素棕榈酸酯盐酸盐用途

Clindamycin palmitate hydrochloride 是克林霉素和棕榈酸酯的水溶性盐酸盐,是一种抗菌药物。Clindamycin palmitate hydrochloride 在体外是无活性的,快速体内水解可以将该化合物转化为抗菌活性克林霉素。

克林霉素棕榈酸酯盐酸盐名称

• 中文名: 棕榈氯林可霉素盐酸盐
• 英文名: Clindamycin Palmitate Hydrochloride
• 中文别名: 盐酸克林霉素棕榈酸酯 | 克林霉素棕榈酸酯盐酸盐

克林霉素棕榈酸酯盐酸盐生物活性

• 描述: Clindamycin palmitate hydrochloride 是克林霉素和棕榈酸酯的水溶性盐酸盐,是一种抗菌药物。Clindamycin palmitate hydrochloride 在体外是无活性的,快速体内水解可以将该化合物转化为抗菌活性克林霉素。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Bharathi Ch, et al. Identification, isolation and characterization of impurities of clindamycin palmitate hydrochloride. J Pharm Biomed Anal. 2008 Dec 1;48(4):1211-8.

克林霉素棕榈酸酯盐酸盐物理化学性质

• 沸点: 767.4ºC at 760 mmHg
• 熔点: 141-143ºC
• 分子式: C₃₄H₆₄Cl₂N₂O₆S
• 分子量: 699.853
• 闪点: 417.9ºC
• 精确质量: 698.386230
• PSA: 133.63000
• LogP: 7.55250
• InChIKey: GTNDZRUWKHDICY-KXROMCTESA-N
• SMILES: CCCCCCCCCCCCCCCC(=O)OC1C(SC)OC(C(NC(=O)C2CC(CCC)CN2C)C(C)Cl)C(O)C1O.Cl
• 蒸汽压: 3.44E-27mmHg at 25°C
• 储存条件: -20°C

克林霉素棕榈酸酯盐酸盐靶点实验

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实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

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实验名称：qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cel... 来源：824 靶标：RecName: Full=ATPase family AAA domain-containing protein 5; AltName: Full=Chromosome fragility-associated gene 1 protein External Id：ELG271

实验名称：qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signal... 来源：824 靶标：thyroid hormone receptor beta isoform 2 [Rattus norvegicus] External Id：TRN186

实验名称：qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signal... 来源：824 靶标：N/A External Id：TRV455

实验名称：qHTS for Inhibitors of binding or entry into cells for Marburg Virus 来源：NCGC 靶标：gene 4 small orf - Marburg virus External Id：VSVM-OFFLINE

实验名称：qHTS for Inhibitors of binding or entry into cells for Lassa Virus 来源：NCGC 靶标：N/A External Id：VSVL-OFFLINE

实验名称：qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell fr... 来源：824 靶标：N/A External Id：SPEC167MG

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克林霉素棕榈酸酯盐酸盐英文别名

• methyl 7-chloro-6,7,8-trideoxy-2-O-hexadecanoyl-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-L-threo-α-D-galacto-octopyranoside hydrochloride
• Methyl (5R)-5-[(1S,2S)-2-chloro-1-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}propyl]-2-O-palmitoyl-1-thio-β-L-arabinopyranoside hydrochloride (1:1)
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-2-O-(1-oxohexadecyl)-1-thio-, hydrochloride (1:1)
• (2R,3R,4S,5R,6R)-6-[(1S,2S)-2-chloro-1-({[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl}amino)propyl]-4,5-dihydroxy-2-(methylsulfanyl)tetrahydro-2H-pyran-3-yl hexadecanoate hydrochloride
• Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-α-D-galacto-octopyranoside 2-palmitate monohydrochloride
• Methyl 7-Chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-a-D-galacto-octopyranoside 2-Palmitate Monohydrochloride
• L-threo-α-D-galacto-octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-2-O-(1-oxohexadecyl)-1-thio-, monohydrochloride
• hexadécanoate de (2R,3R,4S,5R,6R)-6-[(1S,2S)-2-chloro-1-({[(2S,4R)-1-méthyl-4-propylpyrrolidin-2-yl]carbonyl}amino)propyl]-4,5-dihydroxy-2-(méthylsulfanyl)tétrahydro-2H-pyran-3-yle chlorhydrate
• Methyl 7-chloro-6,7,8-trideoxy-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-2-O-palmitoyl-1-thio-L-threo-α-D-galacto-octopyranoside hydrochloride (1:1)
• methyl 7-chloro-6,7,8-trideoxy-2-O-hexadecanoyl-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-L-threo-α-D-galacto-octopyranoside hydrochloride (1:1)
• Methyl (2S-trans)-7-Chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-2-hexadecanoate-L-threo-a-D-galacto-octopyranoside Monohydrochloride
• Clindamycin 2-palmitate hydrochloride
• Clindamycin palmitate hydrochloride
• (2R,3R,4S,5R,6R)-6-[(1S,2S)-2-Chlor-1-({[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl}amino)propyl]-4,5-dihydroxy-2-(methylsulfanyl)tetrahydro-2H-pyran-3-ylhexadecanoathydrochlorid
• U 25179E