P1788

• 常用名: P1788
• 英文名: P1788
• CAS号: 2554623-76-4
• 分子量: 259.30
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₅H₁₇NO₃
• 熔点: N/A
• 闪点: N/A

P1788用途

P1788是一种二氢乳清酸脱氢酶(DHODH)抑制剂。P1788诱导DNA损伤[1]。

P1788名称

• 英文名: P1788

P1788生物活性

• 描述: P1788是一种二氢乳清酸脱氢酶(DHODH)抑制剂。P1788诱导DNA损伤[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 细胞周期/DNA损伤 >> DNA/RNA合成
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Hayek S, et al. Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition. Eur J Med Chem. 2020 Jan 15;186:111855.

P1788物理化学性质

• 分子式: C₁₅H₁₇NO₃
• 分子量: 259.30
• InChIKey: SGSGNCXRTWQHNP-UHFFFAOYSA-N
• SMILES: O=C1OC2(CCCCC2)c2ccn(C3CC3)c(=O)c21

P1788靶点实验

查看更多实验

实验名称：Inhibition of DHODH in human HEK293 cells transfected with ISRE-luciferase reporter g... 来源：ChEMBL 靶标：Dihydroorotate dehydrogenase (quinone), mitochondrial External Id：CHEMBL4682363

实验名称：Inhibition of DHODH in human HEK293 cells transfected with ISRE-luciferase reporter g... 来源：ChEMBL 靶标：Dihydroorotate dehydrogenase (quinone), mitochondrial External Id：CHEMBL4682362

实验名称：Inhibition of DHODH in human HEK293 cells transfected with ISRE-luciferase reporter g... 来源：ChEMBL 靶标：Dihydroorotate dehydrogenase (quinone), mitochondrial External Id：CHEMBL4682365

实验名称：Inhibition of DHODH in human HEK293 cells transfected with ISRE-luciferase reporter g... 来源：ChEMBL 靶标：Dihydroorotate dehydrogenase (quinone), mitochondrial External Id：CHEMBL4682364

实验名称：Inhibition of DHODH in human HEK293 cells transfected with ISRE-luciferase reporter g... 来源：ChEMBL 靶标：Dihydroorotate dehydrogenase (quinone), mitochondrial External Id：CHEMBL4682367

实验名称：Inhibition of DHODH in human HEK293 cells transfected with ISRE-luciferase reporter g... 来源：ChEMBL 靶标：Dihydroorotate dehydrogenase (quinone), mitochondrial External Id：CHEMBL4682366

实验名称：Inhibition of DHODH in human HEK293 cells transfected with ISRE-luciferase reporter g... 来源：ChEMBL 靶标：Dihydroorotate dehydrogenase (quinone), mitochondrial External Id：CHEMBL4682369

实验名称：Inhibition of DHODH in human HEK293 cells transfected with ISRE-luciferase reporter g... 来源：ChEMBL 靶标：Dihydroorotate dehydrogenase (quinone), mitochondrial External Id：CHEMBL4682368

实验名称：Inhibition of DHODH in human HEK293 cells transfected with ISRE-luciferase reporter g... 来源：ChEMBL 靶标：Dihydroorotate dehydrogenase (quinone), mitochondrial External Id：CHEMBL4682355

实验名称：Inhibition of DHODH in human HEK293 cells transfected with ISRE-luciferase reporter g... 来源：ChEMBL 靶标：Dihydroorotate dehydrogenase (quinone), mitochondrial External Id：CHEMBL4682354

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