Loxoprofenol-SRS tromethamine

• 常用名: Loxoprofenol-SRS tromethamine
• 英文名: Loxoprofenol-SRS tromethamine
• CAS号: 2582872-01-1
• 分子量: 369.45
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₃₁NO₆
• 熔点: N/A
• 闪点: N/A

Loxoprofenol-SRS tromethamine用途

洛索洛芬醇SRS氨丁三醇(HR1405-01)是洛索洛菲的活性代谢产物,是一种安全的静脉注射非甾体抗炎药(NSAID),具有优越的抗炎和镇痛活性[1]。

Loxoprofenol-SRS tromethamine名称

• 英文名: Loxoprofenol-SRS tromethamine

Loxoprofenol-SRS tromethamine生物活性

• 描述: 洛索洛芬醇SRS氨丁三醇(HR1405-01)是洛索洛菲的活性代谢产物,是一种安全的静脉注射非甾体抗炎药(NSAID),具有优越的抗炎和镇痛活性[1]。
• 相关类别:
  研究领域 >> 炎症/免疫
  信号通路 >> 免疫及炎症 >> COX
• 参考文献:

  [1]. Hai Ye, et al. HR1405-01, a Safe intravenous NSAID with superior anti-inflammatory and analgesic activities in preclinical trials. Eur J Med Chem. 2022 May 5;235:114258.

Loxoprofenol-SRS tromethamine物理化学性质

• 分子式: C₁₉H₃₁NO₆
• 分子量: 369.45

Loxoprofenol-SRS tromethamine靶点实验

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实验名称：Anti-hyperalgesic activity in carrageenan-induced mechanical hyperalgesia Sprague-Daw... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL5162653

实验名称：Analgesic activity in iv dosed ICR mouse assessed as reduction in acetic acid induced... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5162652

实验名称：Analgesic activity in acetic acid induced ICR mouse assessed as average writhing time... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5162655

实验名称：Antiinflammatory activity in carrageenan-induced Sprague-Dawley rat assessed as paw w... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL5162654

实验名称：Ratio of AUC in female to male in Sprague-Dawley rat at 3 mg/kg by LC-MS/MS analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL5162651

实验名称：Drug metabolism in male Sprague-Dawley rat plasma assessed ascis-(S)-2-(4-(((1R,2R)-2... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5162685

实验名称：Drug metabolism in male Sprague-Dawley rat plasma assessed as trans-(R)-2-(4-(((1S,2R... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5162684

实验名称：Drug metabolism in female Sprague-Dawley rat plasma assessed as trans-(S)-2-(4-(((1S,... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5162687

实验名称：Drug metabolism in male Sprague-Dawley rat plasma assessed as cis-(S)-2-(4-(((1S,2S)-... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5162686

实验名称：Drug metabolism in male Sprague-Dawley rat plasma assessed as cis-(R)-2-(4-(((1R,2R)-... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5162681

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