M1/M4 muscarinic agonist 3

• 常用名: M1/M4 muscarinic agonist 3
• 英文名: M1/M4 muscarinic agonist 3
• CAS号: 2640109-30-2
• 分子量: 402.50
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₃₁FN₂O₃
• 熔点: N/A
• 闪点: N/A

M1/M4 muscarinic agonist 3用途

M1/M4 muscarinic agonist 3 (compound 44) 是毒蕈碱 mAChR M1/M4 激动剂,EC50s 分别为 31 nM 和 9.3 nM。

M1/M4 muscarinic agonist 3名称

• 英文名: M1/M4 muscarinic agonist 3

M1/M4 muscarinic agonist 3生物活性

• 描述: M1/M4 muscarinic agonist 3 (compound 44) 是毒蕈碱 mAChR M1/M4 激动剂,EC50s 分别为 31 nM 和 9.3 nM。
• 相关类别:
  信号通路 >> 神经信号通路 >> mAChR
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 由mAChR
  研究领域 >> 神经疾病
• 靶点实验:

  EC50: 31 nM (M1 muscarinic receptor), 9.3 nM (M4 muscarinic receptor)[1]

• 参考文献:

  [1]. Thomson C G et al. Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists[J]. ACS Medicinal Chemistry Letters, 2023.

M1/M4 muscarinic agonist 3物理化学性质

• 分子式: C₂₃H₃₁FN₂O₃
• 分子量: 402.50

M1/M4 muscarinic agonist 3靶点实验

查看更多实验

实验名称：Activation of human cloned muscarinic M5 receptor expressed in CHO-K1 cells by Calciu... 来源：ChEMBL 靶标：Muscarinic acetylcholine receptor M5 External Id：CHEMBL5393393

实验名称：Activation of human cloned muscarinic M4 receptor expressed in CHO-K1 cells by Calciu... 来源：ChEMBL 靶标：Muscarinic acetylcholine receptor M4 External Id：CHEMBL5393391

实验名称：Activation of human cloned muscarinic M3 receptor expressed in CHO-K1 cells by Calciu... 来源：ChEMBL 靶标：Muscarinic acetylcholine receptor M3 External Id：CHEMBL5393389

实验名称：Activation of human cloned muscarinic M2 receptor expressed in CHO-K1 cells by Calciu... 来源：ChEMBL 靶标：Muscarinic acetylcholine receptor M2 External Id：CHEMBL5393387

实验名称：Activation of human muscarinic M1 receptor expressed in HEK293 cells incubated for 3 ... 来源：ChEMBL 靶标：Muscarinic acetylcholine receptor M1 External Id：CHEMBL5393385

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