CXCR2 antagonist 2

• 常用名: CXCR2 antagonist 2
• 英文名: CXCR2 antagonist 2
• CAS号: 2647464-91-1
• 分子量: 364.39
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₇FN₂O₄S
• 熔点: N/A
• 闪点: N/A

CXCR2 antagonist 2用途

CXCR2拮抗剂2是一种用于癌症免疫治疗的有效CXCR2拮抗剂,IC50值为95 nM。

CXCR2 antagonist 2名称

• 英文名: CXCR2 antagonist 2

CXCR2 antagonist 2生物活性

• 描述: CXCR2拮抗剂2是一种用于癌症免疫治疗的有效CXCR2拮抗剂,IC50值为95 nM。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> CXCR
  信号通路 >> 免疫及炎症 >> CXCR
• 参考文献:

  [1]. Dong Y, et al. Discovery of Benzocyclic Sulfone Derivatives as Potent CXCR2 Antagonists for Cancer Immunotherapy. J Med Chem. 2021 Nov 25;64(22):16626-16640.

CXCR2 antagonist 2物理化学性质

• 分子式: C₁₇H₁₇FN₂O₄S
• 分子量: 364.39
• InChIKey: SBTIRQPCNMRDMN-UHFFFAOYSA-N
• SMILES: Cc1c(F)cccc1NC(=O)Nc1ccc2c(c1O)S(=O)(=O)CCC2

CXCR2 antagonist 2靶点实验

查看更多实验

实验名称：Effect on granulocytic MDSCs level in mouse xenografted with human Panc02 cells at 10... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5033834

实验名称：Antitumour activity against mouse Panc02 cells xenografted in mouse assessed as reduc... 来源：ChEMBL 靶标：Panc02 External Id：CHEMBL5033833

实验名称：Antitumour activity against mouse Panc02 cells xenografted in mouse assessed as reduc... 来源：ChEMBL 靶标：Panc02 External Id：CHEMBL5033832

实验名称：Antitumour activity against mouse Panc02 cells xenografted in mouse assessed as chang... 来源：ChEMBL 靶标：Panc02 External Id：CHEMBL5033831

实验名称：Antitumour activity against mouse Panc02 cells xenografted in mouse assessed as upreg... 来源：ChEMBL 靶标：Panc02 External Id：CHEMBL5033835

实验名称：Antitumour activity against mouse Panc02 cells xenografted in mouse assessed as chang... 来源：ChEMBL 靶标：Panc02 External Id：CHEMBL5033826

实验名称：Antitumour activity against mouse Panc02 cells xenografted in mouse assessed as chang... 来源：ChEMBL 靶标：Panc02 External Id：CHEMBL5033825

实验名称：Antitumour activity against mouse Panc02 cells xenografted in mouse assessed as chang... 来源：ChEMBL 靶标：Panc02 External Id：CHEMBL5033824

实验名称：Antitumour activity against mouse Panc02 cells xenografted in mouse assessed as chang... 来源：ChEMBL 靶标：Panc02 External Id：CHEMBL5033823

实验名称：Antitumour activity against mouse Panc02 cells xenografted in mouse assessed as chang... 来源：ChEMBL 靶标：Panc02 External Id：CHEMBL5033830

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