吲哌胺

• 常用名: 吲哌胺
• 英文名: Indoramin
• CAS号: 26844-12-2
• 分子量: 347.45300
• 密度: 1.21g/cm3
• 沸点: 600ºC at 760mmHg
• 分子式: C₂₂H₂₅N₃O
• 熔点: 208-210°
• 闪点: 316.7ºC

吲哌胺用途

吲哚美辛是一种口服活性抗高血压药物。吲哚美辛对α1A肾上腺素受体也有选择性[1]。

吲哌胺名称

• 中文名: 吲哚拉明
• 英文名: N-[1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl]benzamide
• 中文别名: 3-[2-(4-苯酰胺-1-哌啶)乙基]吲哚 | 吲哌胺

吲哌胺生物活性

• 描述: 吲哚美辛是一种口服活性抗高血压药物。吲哚美辛对α1A肾上腺素受体也有选择性[1]。
• 相关类别:
  研究领域 >> 内分泌
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体
• 参考文献:

  [1]. M Eltze, et al. In functional experiments, risperidone is selective, not for the B, but for the A subtype of alpha 1-adrenoceptors. Eur J Pharmacol. 1996 Jan 4;295(1):69-73.

吲哌胺物理化学性质

• 密度: 1.21g/cm3
• 沸点: 600ºC at 760mmHg
• 熔点: 208-210°
• 分子式: C₂₂H₂₅N₃O
• 分子量: 347.45300
• 闪点: 316.7ºC
• 精确质量: 347.20000
• PSA: 48.13000
• LogP: 3.93360
• InChIKey: JXZZEXZZKAWDSP-UHFFFAOYSA-N
• SMILES: O=C(NC1CCN(CCc2c[nH]c3ccccc23)CC1)c1ccccc1
• 蒸汽压: 2.36E-14mmHg at 25°C
• 折射率: 1.657

吲哌胺毒性和生态

吲哌胺安全信息

• 海关编码: 2933990090

吲哌胺海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

吲哌胺靶点实验

查看更多实验

实验名称：Binding affinity against Alpha-1D adrenergic receptor, from human clones. 来源：ChEMBL 靶标：Alpha-1D adrenergic receptor External Id：CHEMBL643573

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Partition coefficient (logD6.5) 来源：ChEMBL 靶标：N/A External Id：CHEMBL646647

实验名称：Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste... 来源：Broad Institute 靶标：N/A External Id：7124-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

实验名称：Delta logD (logD6.5 - logD7.4) 来源：ChEMBL 靶标：N/A External Id：CHEMBL636394

实验名称：Percentage fall in systolic blood pressure after 2 hr at 25 mg/kg given perorally 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL795039

实验名称：Apparent partition coefficient was measured as histamine releasing activity in rat ma... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL797214

共237条，当前第1页，共24页

1

2

3

4

5

吲哌胺英文别名

• 3-<2-(4-Benzamidopiperid-1-yl)ethyl>indol
• Indoramine [INN-French]
• N-[1-(2-indol-3-yl-ethyl)-piperidin-4-yl]-benzamide
• 3-[2-(4-benzamido-1-piperidyl)ethyl]indole
• INDORAMIN
• Indoramine
• 3-[2-(4-benzamidopiperid-1-yl)ethyl]indole
• Indoramina [INN-Spanish]
• EINECS 248-041-5
• Benzamide,N-(1-(2-(1H-indol-3-yl)ethyl)-4-piperidinyl)
• Indoraminum [INN-Latin]