Cyclo(-Pro-Val)

• 常用名: Cyclo(-Pro-Val)
• 英文名: Cyclo(-Pro-Val)
• CAS号: 2854-40-2
• 分子量: 196.25
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₀H₁₆N₂O₂
• 熔点: N/A
• 闪点: N/A

Cyclo(-Pro-Val)用途

环(L-Pro-L-Val)是一种2,5-二酮哌嗪,对植物病原微生物(如R.fascians LMG 3605)具有毒性活性。Cyclo(L-Pro-L-Val)的毒性与浓度相当的氯霉素(HY-B0239)相似。Cyclo(L-Pro-L-Val)也能抑制革兰氏阳性植物病原菌。环(L-Pro-L-Val)作为生物农药具有潜在的开发潜力[1]。

Cyclo(-Pro-Val)名称

• 英文名: (3S,8aS)-3-propan-2-yl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Cyclo(-Pro-Val)生物活性

• 描述: 环(L-Pro-L-Val)是一种2,5-二酮哌嗪,对植物病原微生物(如R.fascians LMG 3605)具有毒性活性。Cyclo(L-Pro-L-Val)的毒性与浓度相当的氯霉素(HY-B0239)相似。Cyclo(L-Pro-L-Val)也能抑制革兰氏阳性植物病原菌。环(L-Pro-L-Val)作为生物农药具有潜在的开发潜力[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Cimmino A, et al. Isolation of 2,5-diketopiperazines from Lysobacter capsici AZ78 with activity against Rhodococcus fascians. Nat Prod Res. 2021 Dec;35(23):4969-4977.

Cyclo(-Pro-Val)物理化学性质

• 分子式: C₁₀H₁₆N₂O₂
• 分子量: 196.25
• 精确质量: 196.12100
• PSA: 49.41000
• LogP: 0.39850
• InChIKey: XLUAWXQORJEMBD-YUMQZZPRSA-N
• SMILES: CC(C)C1NC(=O)C2CCCN2C1=O
• 储存条件: -20°C，密闭，干燥

Cyclo(-Pro-Val)安全信息

• 海关编码: 2933990090

Cyclo(-Pro-Val)海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Cyclo(-Pro-Val)靶点实验

查看更多实验

实验名称：Anti-inflammatory activity in human neutrophils assessed as inhibition of FMLP/CB-ind... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1826242

实验名称：Displacement of [3H]substance P from NK1 receptor in human astrocytoma cells at 200 u... 来源：ChEMBL 靶标：Substance-P receptor External Id：CHEMBL941113

实验名称：Antibacterial activity against Bacillus cereus after 2 days by disk assay 来源：ChEMBL 靶标：Bacillus cereus External Id：CHEMBL1028402

实验名称：Antibacterial activity against Micrococcus luteus after 2 days by disk assay 来源：ChEMBL 靶标：Micrococcus luteus External Id：CHEMBL1028403

实验名称：Antioxidant activity assessed DPPH scavenging activity at 500 uM 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1826537

实验名称：Inhibition of recombinant human P-gp ATPase activity in presence of MgATP preincubate... 来源：ChEMBL 靶标：ATP-dependent translocase ABCB1 External Id：CHEMBL5107730

实验名称：Cytotoxicity against human HCT-116 cells assessed as reduction on cell viability at 1... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL5107727

实验名称：Cytotoxicity against human wild type HCT-116 cells assessed as reduction on cell viab... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL5107728

实验名称：Cytotoxicity against paclitaxel-resistant human HCT116tax cells assessed as reduction... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5107729

实验名称：Antibacterial activity against Escherichia coli ATCC 25922 after 18 hrs by agar diffu... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL3602538

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Cyclo(-Pro-Val)英文别名

• Cyclo(-Pro-Val)
• cyclo-(L-Val-L-Pro)
• cyclo(-L-pro-L-val-)
• (3S,8aS)-3-Isopropylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione