S 14506 盐酸盐

• 常用名: S 14506 盐酸盐
• 英文名: S 14506 hydrochloride
• CAS号: 286369-38-8
• 分子量: 443.941
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₂₇ClFN₃O₂
• 熔点: N/A
• 闪点: N/A

S 14506 盐酸盐用途

S-14506盐酸盐是一种有效的5-HT1A激动剂。S-14506盐酸盐通过阻断多巴胺D2受体显示多巴胺拮抗剂特性。S-14506盐酸盐抑制纹状体和嗅球中[3H]雷氯普胺的体内结合。S-14506盐酸盐具有抗焦虑剂研究的潜力[1][2]。

S 14506 盐酸盐名称

• 中文名: S 14506 盐酸盐
• 英文名: S 14506 hydrochloride

S 14506 盐酸盐生物活性

• 描述: S-14506盐酸盐是一种有效的5-HT1A激动剂。S-14506盐酸盐通过阻断多巴胺D2受体显示多巴胺拮抗剂特性。S-14506盐酸盐抑制纹状体和嗅球中[3H]雷氯普胺的体内结合。S-14506盐酸盐具有抗焦虑剂研究的潜力[1][2]。
• 相关类别:
  研究领域 >> 其他
  研究领域 >> 神经疾病
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 5-HT受体
  信号通路 >> 神经信号通路 >> 5-HT受体
• 参考文献:

  [1]. Francis C. Colpaert, et al. S 14506: A novel, potent, high-efficacy 5-HT1A agonist and potential anxiolytic agent. 1992, 21-48.

  [2]. Protais P, et al. Dopamine receptor antagonist properties of S 14506, 8-OH-DPAT, raclopride and clozapine in rodents. Eur J Pharmacol. 1994 Dec 12;271(1):167-77.

S 14506 盐酸盐物理化学性质

• 分子式: C₂₄H₂₇ClFN₃O₂
• 分子量: 443.941
• 精确质量: 443.177582
• 储存条件: -20°C， 干燥

S 14506 盐酸盐靶点实验

查看更多实验

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：Tocris HTS for Inhibitors of Aerobactin Synthetase lucA 来源：23265 External Id：IucA Pilot Assay Tocris Library

共4条，当前第1页，共1页

1

S 14506 盐酸盐英文别名

• S-14506 HYDROCHLORIDE
• 4-Fluoro-N-{2-[4-(7-methoxy-1-naphthyl)-1-piperazinyl]ethyl}benzamide hydrochloride (1:1)
• MFCD00910294
• Benzamide, 4-fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl]ethyl]-, hydrochloride (1:1)
• 4-Fluoro-N-{2-[4-(7-methoxy-1-naphthyl)piperazin-1-yl]ethyl}benzamide hydrochloride (1:1)
• 4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide hydrochloride