MMP-7-IN-3

• 常用名: MMP-7-IN-3
• 英文名: MMP-7-IN-3
• CAS号: 2865097-58-9
• 分子量: 818.26
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₄H₄₃ClF₃N₇O₉S
• 熔点: N/A
• 闪点: N/A

MMP-7-IN-3用途

MMP-7-IN-3 是一种有效的 MMP-7 选择性抑制剂。MMP-7-IN-3 在单侧输尿管梗阻小鼠模型中抑制了肾纤维化进展。

MMP-7-IN-3名称

• 英文名: MMP-7-IN-3

MMP-7-IN-3生物活性

• 描述: MMP-7-IN-3 是一种有效的 MMP-7 选择性抑制剂。MMP-7-IN-3 在单侧输尿管梗阻小鼠模型中抑制了肾纤维化进展。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 代谢酶/蛋白酶 >> MMP
• 参考文献:

  [1]. Abe-Sato K, et al. Structure-Based Optimization and Biological Evaluation of Potent and Selective MMP-7 Inhibitors for Kidney Fibrosis. J Med Chem. 2023 Oct 20.

MMP-7-IN-3物理化学性质

• 分子式: C₃₄H₄₃ClF₃N₇O₉S
• 分子量: 818.26

MMP-7-IN-3靶点实验

查看更多实验

实验名称：Selectivity ratio of IC50 for inhibition of recombinant human MMP9 to IC50 for inhibi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5374290

实验名称：Selectivity ratio of IC50 for inhibition of recombinant human MMP12 to IC50 for inhib... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5374291

实验名称：Selectivity ratio of IC50 for inhibition of recombinant human MMP3 to IC50 for inhibi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5374288

实验名称：Selectivity ratio of IC50 for inhibition of recombinant human MMP8 to IC50 for inhibi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5374289

实验名称：Selectivity ratio of IC50 for inhibition of recombinant human MMP1 to IC50 for inhibi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5374286

实验名称：Selectivity ratio of IC50 for inhibition of recombinant human MMP2 to IC50 for inhibi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5374287

实验名称：Metabolic stability in human serum assessed as parent compound remaining at 5 uM incu... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5374285

实验名称：Inhibition of recombinant human MMP14 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-A... 来源：ChEMBL 靶标：Matrix metalloproteinase-14 External Id：CHEMBL5374278

实验名称：Inhibition of recombinant human MMP7 using MOCAc-Pro-Leu-Gly-Leu-A2pr-(Dnp)-Ala-Arg-N... 来源：ChEMBL 靶标：Matrilysin External Id：CHEMBL5374277

实验名称：Total clearance in rat at 1 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL5540398

共29条，当前第1页，共3页

1

2

3