Anti-inflammatory agent 46

• 常用名: Anti-inflammatory agent 46
• 英文名: Anti-inflammatory agent 46
• CAS号: 2925586-96-3
• 分子量: 434.48
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₁₉FN₂O₃S
• 熔点: N/A
• 闪点: N/A

Anti-inflammatory agent 46用途

抗炎剂46(化合物7h)是具有一氧化氮(NO)抑制作用的抗炎剂。抗炎剂46以低能量与iNOS结合,抑制小鼠肿胀(剂量为10 mg/kg)[1]。

Anti-inflammatory agent 46名称

• 英文名: Anti-inflammatory agent 46

Anti-inflammatory agent 46生物活性

• 描述: 抗炎剂46(化合物7h)是具有一氧化氮(NO)抑制作用的抗炎剂。抗炎剂46以低能量与iNOS结合,抑制小鼠肿胀(剂量为10 mg/kg)[1]。
• 相关类别:
  信号通路 >> 免疫及炎症 >> 一氧化氮合酶
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Akhtar M, et al. Anti-inflammatory efficacy and relevant SAR investigations of novel chiral pyrazolo isoquinoline derivatives: Design, synthesis, in-vitro, in-vivo, and computational studies targeting iNOS. Eur J Med Chem. 2023 Aug 5;256:115412.

Anti-inflammatory agent 46物理化学性质

• 分子式: C₂₄H₁₉FN₂O₃S
• 分子量: 434.48

Anti-inflammatory agent 46靶点实验

查看更多实验

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实验名称：Antiinflammatory activity against xylene-induced ear edema mouse model assessed as sw... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5370728

实验名称：Anti inflammatory activity in LPS-induced mouse RAW264.7 cells assessed as inhibition... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5370726

实验名称：Anti inflammatory activity in LPS-induced mouse RAW264.7 cells assessed as inhibition... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5370725

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