苯他西泮结构式
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常用名 | 苯他西泮 | 英文名 | Bentazepam |
|---|---|---|---|---|
| CAS号 | 29462-18-8 | 分子量 | 296.38700 | |
| 密度 | 1.38g/cm3 | 沸点 | 532.6ºC at 760 mmHg | |
| 分子式 | C17H16N2OS | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 275.9ºC |
苯他西泮用途苯他西泮(噻吩)是一种具有短效抗焦虑作用的化合物。苯他西泮具有抗惊厥和镇静作用。苯他西泮可用于抑郁症和焦虑症的研究[1]。 |
| 中文名 | 苯他西泮 |
|---|---|
| 英文名 | 5-phenyl-3,4,6,7,8,9-hexahydro-[1]benzothiolo[2,3-e][1,4]diazepin-2-one |
| 英文别名 | 更多 |
| 密度 | 1.38g/cm3 |
|---|---|
| 沸点 | 532.6ºC at 760 mmHg |
| 分子式 | C17H16N2OS |
| 分子量 | 296.38700 |
| 闪点 | 275.9ºC |
| 精确质量 | 296.09800 |
| PSA | 69.70000 |
| LogP | 2.99000 |
| InChIKey | AIZFEOPQVZBNGH-UHFFFAOYSA-N |
| SMILES | O=C1CN=C(c2ccccc2)c2c(sc3c2CCCC3)N1 |
| 蒸汽压 | 2E-11mmHg at 25°C |
| 折射率 | 1.733 |
| 储存条件 | 通风低温干燥 |
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苯他西泮 29462-18-8 |
| 文献:Tinney; Sanchez; Nogas Journal of Medicinal Chemistry, 1974 , vol. 17, # 6 p. 624 - 630 |
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苯他西泮 29462-18-8 |
| 文献:Nakanishi,M. et al. Journal of Medicinal Chemistry, 1973 , vol. 16, p. 214 - 219 |
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苯他西泮 29462-18-8 |
| 文献:Heckendorn; Gagneux Tetrahedron Letters, 1973 , vol. 25, p. 2279 - 2282 |
| 苯他西泮上游产品 3 | |
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| 苯他西泮下游产品 0 | |
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实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
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实验名称:Binding affinity towards human GABRA1 in an in vitro assay with cellular components m...
来源:ChEMBL
靶标:Gamma-aminobutyric acid receptor subunit gamma-2
External Id:CHEMBL5291799
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实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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实验名称:QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源:The Scripps Research Institute Molecular Screening Center
靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
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实验名称:Luminescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of ADP-glo R...
来源:Broad Institute
靶标:N/A
External Id:2046-03_INHIBITORS_DOSE-TITRATION_MLPCN-CHERRYPICK
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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实验名称:Binding affinity towards human ESR1 in an in vitro cell free assay (CRO assay) measur...
来源:ChEMBL
靶标:Estrogen receptor
External Id:CHEMBL5291792
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实验名称:Compound was evaluated for inhibition of human F2 in an in vitro cell free assay meas...
来源:ChEMBL
靶标:Prothrombin
External Id:CHEMBL5291794
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实验名称:Luminescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of Glycogen Syn...
来源:Broad Institute
靶标:glycogen synthase kinase 3 beta isoform 1 [Homo sapiens]
External Id:2046-02_INHIBITORS_DOSE-TITRATION_MLPCN-CHERRYPICK
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| Bentazepam |
| CI-718 |
| Tiadipone |
| Thiadipone |
| 1,3,6,7,8,9-Hexahydro-5-phenyl-2H-(1)benzothieno(2,3-e)-1,4-diazepin-2-one |
| QM-6008 |
| 5-phenyl-1,3,6,7,8,9-hexahydro-benzo[4,5]thieno[2,3-e][1,4]diazepin-2-one |
| Bentazepamum [INN-Latin] |
| 2H-(1)BENZOTHIENO(2,3-e)-1,4-DIAZEPIN-2-ONE,1,3,6,7,8,9-HEXAHYDRO-5-PHENYL |