ROCK2-IN-7

• 常用名: ROCK2-IN-7
• 英文名: ROCK2-IN-7
• CAS号: 3000541-95-4
• 分子量: 445.53
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₂₈FN₅O
• 熔点: N/A
• 闪点: N/A

ROCK2-IN-7用途

ROCK2-IN-7 是一种以 ROCK2 为靶点的激酶抑制剂。ROCK2-IN-7 抑制 ROCK2/pSTAT3 信号通路。ROCK2-IN-7 在银屑病模型中可抑制全身免疫激活并减轻炎症反应。

ROCK2-IN-7名称

• 英文名: ROCK2-IN-7

ROCK2-IN-7生物活性

• 描述: ROCK2-IN-7 是一种以 ROCK2 为靶点的激酶抑制剂。ROCK2-IN-7 抑制 ROCK2/pSTAT3 信号通路。ROCK2-IN-7 在银屑病模型中可抑制全身免疫激活并减轻炎症反应。
• 相关类别:
  信号通路 >> 干细胞及 Wnt 通路 >> STAT
  信号通路 >> JAK/STAT信号通路 >> STAT
  研究领域 >> 其他
  信号通路 >> 细胞周期/DNA损伤 >> 岩石
  信号通路 >> 代谢酶/蛋白酶 >> MMP
  信号通路 >> 干细胞及 Wnt 通路 >> 岩石
  信号通路 >> TGF-beta/Smad 信号通路 >> 岩石
• 靶点实验:

  ROCK2

  MMP-2

  Stat-3

• 参考文献:

  [1]. Huang, Yun, et al. "Design, Synthesis, and Biological Evaluation of an Orally Bioavailable, Potent, and Selective ROCK2 Inhibitor for Psoriasis Treatment." Journal of Medicinal Chemistry (2023)

ROCK2-IN-7物理化学性质

• 分子式: C₂₆H₂₈FN₅O
• 分子量: 445.53

ROCK2-IN-7靶点实验

查看更多实验

实验名称：Anti-inflammatory activity in Balb/c mouse model of IMQ-induced skin inflammation ass... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5392691

实验名称：Anti-inflammatory activity in Balb/c mouse model of IMQ-induced skin inflammation ass... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5392690

实验名称：Anti-inflammatory activity in Balb/c mouse model of IMQ-induced skin inflammation ass... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5392689

实验名称：Anti-inflammatory activity in Balb/c mouse model of IMQ-induced skin inflammation ass... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5392688

实验名称：Anti-inflammatory activity in Balb/c mouse model of IMQ-induced skin inflammation ass... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5392687

实验名称：Anti-inflammatory activity in Balb/c mouse model of IMQ-induced skin inflammation ass... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5392686

实验名称：Anti-inflammatory activity in Balb/c mouse model of IMQ-induced skin inflammation ass... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5392685

实验名称：Anti-inflammatory activity in Balb/c mouse model of IMQ-induced skin inflammation ass... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5392684

实验名称：Anti-inflammatory activity in Balb/c mouse model of IMQ-induced skin inflammation ass... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5392683

实验名称：Anti-inflammatory activity in Balb/c mouse model of IMQ-induced skin inflammation ass... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5392682

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