IQ 1

• 常用名: IQ 1
• 英文名: IQ-1
• CAS号: 331001-62-8
• 分子量: 362.425
• 密度: 1.2±0.1 g/cm3
• 沸点: 591.2±50.0 °C at 760 mmHg
• 分子式: C₂₁H₂₂N₄O₂
• 熔点: N/A
• 闪点: 311.4±30.1 °C
• 符号: GHS07
• 信号词: Warning

IQ 1用途

IQ 1 有很多作用，例如降低Wnt刺激的磷酸化，保持小鼠ESCs的多功能性，阻止PP2A/Nkd的相互作用等等。

IQ 1名称

• 中文名: IQ 1
• 英文名: (2E)-2-[(E)-(4-Acetylphenyl)diazenyl]-2-(3,3-dimethyl-3,4-dihydro-1(2H)-isoquinolinylidene)acetamide

IQ 1生物活性

• 描述: IQ 1 有很多作用,例如降低Wnt刺激的磷酸化,保持小鼠ESCs的多功能性,阻止PP2A/Nkd的相互作用等等。
• 相关类别:
  信号通路 >> 干细胞及 Wnt 通路 >> Wnt信号
  研究领域 >> 癌症
• 参考文献:

  [1]. Miyabayashi T et al. Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency. Proc Natl Acad Sci U S A, 2007 Mar 27, 104(13):5668-73.

IQ 1物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 591.2±50.0 °C at 760 mmHg
• 分子式: C₂₁H₂₂N₄O₂
• 分子量: 362.425
• 闪点: 311.4±30.1 °C
• 精确质量: 362.174286
• LogP: 3.45
• InChIKey: ALJIEVIJBAJISI-PLRJNAJWSA-N
• SMILES: CC(=O)c1ccc(NN=C(C(N)=O)C2=NC(C)(C)Cc3ccccc32)cc1
• 外观性状: 粉末
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.631
• 储存条件: -20℃

IQ 1安全信息

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 危险品运输编码: NONH for all modes of transport

IQ 1靶点实验

查看更多实验

实验名称：A screen for small molecule inhibitors of the human deubiquitinating enzyme, UCH37 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：ubiquitin C-terminal hydrolase UCH37 [Homo sapiens] External Id：HMS937_MLP

实验名称：A screen for compounds that inhibit growth of Escherichia coli 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1158_MLP

实验名称：A screen for compounds that are lethal to S. aureus RN4220 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1364-MLP_WT

实验名称：A screen for compounds that are lethal to S. aureus RN4220 with the processive glycos... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1364-MLP_ugtP

实验名称：High throughput screen for small molecule inhibitors of a hypoxia-regulated fluoresce... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1149-MLP

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IQ 1英文别名

• (2E)-2-[(E)-(4-Acetylphenyl)diazenyl]-2-(3,3-dimethyl-3,4-dihydro-1(2H)-isoquinolinylidene)acetamide
• IQ-1
• IQ 1